DNA that has been recovered from archaeological and palaeontological remains makes it
possible to go back in time and study the genetic relationships of extinct organisms to their …

Owing to their constant low temperatures, glacial ice and permafrost might contain the oldest
nucleic acids and microbial cells on Earth, which could prove key to reconstructing past …

The discovery of antibiotics more than 70 years ago initiated a period of drug innovation
and implementation in human and animal health and agriculture. These discoveries were …

At the recent 5th International Ancient DNA Conference in Manchester, UK, re-ported by Erik
Stokstad in his News Focus article “Divining diet and disease from DN”(28 Jul., p. 530), one …

… Poinar for constructive comments on earlier versions of the manuscript. We also thank S.
Pääbo and the Max Planck Institute of Evolutionary Anthropology for use of their clean room …

We sequenced 28 million base pairs of DNA in a metagenomics approach, using a woolly
mammoth (Mammuthus primigenius) sample from Siberia. As a result of exceptional sample …

DNA from excrements can be amplified by means of the polymerase chain reaction. However,
this has not been possible with ancient feces. Cross-links between reducing sugars and …

The extent of racemization of aspartic acid, alanine, and leucine provides criteria for assessing
whether ancient tissue samples contain endogenous DNA. In samples in which the D/L …

It is difficult to obtain fossil data from the 10% of Earth's terrestrial surface that is covered by
thick glaciers and ice sheets, and hence, knowledge of the paleoenvironments of these …

… We thank all members of the Barreiro laboratory and the Poinar laboratory for their constructive
comments and … Poinar for continued support and manuscript suggestions and editing. …