User profiles for H. M. Ollila
Hanna M. OllilaFIMM-EMBL, Helsinki, Massachusetts General Hospital, Harvard and Broad Institute. Verified email at stanford.edu Cited by 5866 |
Narcolepsy
Narcolepsy is a chronic sleep disorder that has a typical onset in adolescence and is
characterized by excessive daytime sleepiness, which can have severe consequences for the …
characterized by excessive daytime sleepiness, which can have severe consequences for the …
[HTML][HTML] FinnGen provides genetic insights from a well-phenotyped isolated population
Population isolates such as those in Finland benefit genetic research because deleterious
alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor …
alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor …
FinnGen: Unique genetic insights from combining isolated population and national health register data
Population isolates such as Finland provide benefits in genetic studies because the allelic
spectrum of damaging alleles in any gene is often concentrated on a small number of low-…
spectrum of damaging alleles in any gene is often concentrated on a small number of low-…
[HTML][HTML] Face masks to prevent transmission of respiratory infections: Systematic review and meta-analysis of randomized controlled trials on face mask use
HM Ollila, M Partinen, J Koskela, J Borghi… - PloS one, 2022 - journals.plos.org
Objectives To examine the use of face mask intervention in mitigating the risk of spreading
respiratory infections and whether the effect of face mask intervention differs in different …
respiratory infections and whether the effect of face mask intervention differs in different …
Association between telomere length and risk of cancer and non-neoplastic diseases: a Mendelian randomization study
…, H Dommisch, AS Schaefer, F Han, HM Ollila… - JAMA …, 2017 - jamanetwork.com
Importance The causal direction and magnitude of the association between telomere length
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …
Genetics of 35 blood and urine biomarkers in the UK Biobank
Clinical laboratory tests are a critical component of the continuum of care. We evaluate the
genetic basis of 35 blood and urine laboratory measurements in the UK Biobank (n = 363,228 …
genetic basis of 35 blood and urine laboratory measurements in the UK Biobank (n = 363,228 …
Autoimmunity in narcolepsy
Narcolepsy is a severe sleep disorder, in which neurons producing orexin/hypocretin in the
hypothalamus are destroyed. The core symptoms of narcolepsy are debilitating, extreme …
hypothalamus are destroyed. The core symptoms of narcolepsy are debilitating, extreme …
Genetic background of extreme violent behavior
J Tiihonen, MR Rautiainen, HM Ollila… - Molecular …, 2015 - nature.com
In developed countries, the majority of all violent crime is committed by a small group of
antisocial recidivistic offenders, but no genes have been shown to contribute to recidivistic …
antisocial recidivistic offenders, but no genes have been shown to contribute to recidivistic …
Sleep apnoea is a risk factor for severe COVID-19
Background Obstructive sleep apnoea (OSA) is associated with higher body mass index (BMI),
diabetes, older age and male gender, which are all risk factors for severe COVID-19. We …
diabetes, older age and male gender, which are all risk factors for severe COVID-19. We …
Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy
T Karpanen, M Bry, HM Ollila… - Circulation …, 2008 - Am Heart Assoc
Vascular endothelial growth factor (VEGF)-B is poorly angiogenic but prominently expressed
in metabolically highly active tissues, including the heart. We produced mice expressing a …
in metabolically highly active tissues, including the heart. We produced mice expressing a …