Genetic correlations estimated from genome-wide association studies (GWASs) reveal
pervasive pleiotropy across a wide variety of phenotypes. We introduce genomic structural …

Cannabis use is a heritable trait that has been associated with adverse mental health outcomes.
In the largest genome-wide association study (GWAS) for lifetime cannabis use to date (…

There are substantial differences, or variation, between humans in aggression, with its
molecular genetic basis mostly unknown. This review summarizes knowledge on the genetic …

We introduce two novel methods for multivariate genome-wide-association meta-analysis (GWAMA)
of related traits that correct for sample overlap. A broad range of simulation …

We interrogate the joint genetic architecture of 11 major psychiatric disorders at biobehavioral,
functional genomic and molecular genetic levels of analysis. We identify four broad …

Little is known about the genetic architecture of traits affecting educational attainment other
than cognitive ability. We used genomic structural equation modeling and prior genome-wide …

Humans are social animals that experience intense suffering when they perceive a lack of
social connection. Modern societies are experiencing an epidemic of loneliness. Although the …

Background In recent years, there was an increasing popularity in applying artificial intelligence
in the medical field from computer-aided diagnosis (CAD) to patient prognosis prediction…

Childhood aggressive behavior (AGG) has a substantial heritability of around 50%. Here we
present a genome-wide association meta-analysis (GWAMA) of childhood AGG, in which all …

DNA methylation profiles of aggressive behavior may capture lifetime cumulative effects of
genetic, stochastic, and environmental influences associated with aggression. Here, we …