Diabetes, hypertension, body mass index, smoking and COVID-19-related mortality: a systematic review and meta-analysis of observational studies

…, N Laouali, N Peiffer-Smadja, D Aune, G Severi - BMJ open, 2021 - bmjopen.bmj.com
Objectives We conducted a systematic literature review and meta-analysis of observational
studies to investigate the association between diabetes, hypertension, body mass index (BMI…

The epidemiology of prostate cancer

P Boyle, G Severi, GG Giles - Urologic Clinics, 2003 - urologic.theclinics.com
Prostate cancer has become the most common cancer of males in several developed countries.
With increasing age, most men will develop microscopic foci of prostate cancer whether …

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

…, GS Dite, C Apicella, H Tsimiklis, GG Giles, G Severi… - Nature …, 2013 - nature.com
Breast cancer is the most common cancer among women. Common variants at 27 loci have
been identified as associated with susceptibility to breast cancer, and these account for ∼9…

[HTML][HTML] Socioeconomic status and the 25× 25 risk factors as determinants of premature mortality: a multicohort study and meta-analysis of 1· 7 million men and …

…, JR Valverde, C Sacerdote, R Satolli, G Severi… - The Lancet, 2017 - thelancet.com
Background In 2011, WHO member states signed up to the 25 × 25 initiative, a plan to cut
mortality due to non-communicable diseases by 25% by 2025. However, socioeconomic …

[HTML][HTML] Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis …

…, JE Olson, L Baglietto, GG Giles, G Severi… - PLoS …, 2010 - journals.plos.org
Background Immunohistochemical markers are often used to classify breast cancer into
subtypes that are biologically distinct and behave differently. The aim of this study was to …

Multiple newly identified loci associated with prostate cancer susceptibility

…, J Morrison, HI Field, MC Southey, G Severi… - Nature …, 2008 - nature.com
Prostate cancer is the most common cancer affecting males in developed countries. It shows
consistent evidence of familial aggregation, but the causes of this aggregation are mostly …

Measures of familial aggregation depend on definition of family history: meta-analysis for colorectal cancer

L Baglietto, MA Jenkins, G Severi, GG Giles… - Journal of clinical …, 2006 - Elsevier
OBJECTIVE: Familial aggregation, a primary theme in genetic epidemiology, can be estimated
from family studies based on an index person. The excess risk due to the presence of …

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

…, GG Giles, CA McLean, G Severi… - Journal of the …, 2011 - academic.oup.com
Background Previous studies have suggested that breast cancer risk factors are associated
with estrogen receptor (ER) and progesterone receptor (PR) expression status of the tumors. …

Detectable clonal mosaicism and its relationship to aging and cancer

…, BS Melin, U Peters, AM Ruder, HD Sesso, G Severi… - Nature …, 2012 - nature.com
In an analysis of 31,717 cancer cases and 26,136 cancer-free controls from 13 genome-wide
association studies, we observed large chromosomal abnormalities in a subset of clones in …

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

…, FC Hamdy, JL Donovan, K Muir, GG Giles, G Severi… - Nature …, 2013 - nature.com
Prostate cancer is the most frequently diagnosed cancer in males in developed countries.
To identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a …