Case research has commanded respect in the information systems (IS) discipline for at least
a decade. Notwithstanding the relevance and potential value of case studies, this …

In this article we develop a typology of review types and provide a descriptive insight into the
most common reviews found in top IS journals. Our assessment reveals that the number of …

Genome-wide association studies (GWAS) involve testing genetic variants across the
genomes of many individuals to identify genotype–phenotype associations. GWAS have …

Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density
lipoprotein cholesterol and triglycerides are among the most important risk factors for …

Most common human traits and diseases have a polygenic pattern of inheritance: DNA
sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA…

Background Stroke is a leading cause of death and disability, especially in low-income and
middle-income countries. We sought to quantify the importance of potentially modifiable risk …

High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease.
We report the largest genetic association study of blood pressure traits (systolic, diastolic …

Chronic kidney disease (CKD) is a significant public health problem, and recent genetic studies
have identified common CKD susceptibility variants. The CKDGen consortium performed …

Background Embolic strokes of undetermined source represent 20% of ischemic strokes and
are associated with a high rate of recurrence. Anticoagulant treatment with rivaroxaban, an …

Chronic kidney disease (CKD) has a heritable component and is an important global public
health problem because of its high prevalence and morbidity 1 . We conducted genome-…