User profiles for G. McVicker
Graham McVickerAssociate Professor, Salk Institute Verified email at salk.edu Cited by 5432 |
An overview of Ensembl
…, S Keenan, H Lehvaslaiho, G McVicker… - Genome …, 2004 - genome.cshlp.org
Ensembl ( http://www.ensembl.org/ ) is a bioinformatics project to organize biological
information around the sequences of large genomes. It is a comprehensive source of stable …
information around the sequences of large genomes. It is a comprehensive source of stable …
[PDF][PDF] Impact of genetic polymorphisms on human immune cell gene expression
While many genetic variants have been associated with risk for human diseases, how these
variants affect gene expression in various cell types remains largely unknown. To address …
variants affect gene expression in various cell types remains largely unknown. To address …
The Ensembl core software libraries
… This was originally developed as an output format from Exonerate (G. Slater, unpubl.)
and is known by its original acronym “cigar” (concise idiosyncratic gapped alignment report). …
and is known by its original acronym “cigar” (concise idiosyncratic gapped alignment report). …
Brain cell type–specific enhancer–promoter interactome maps and disease-risk association
Noncoding genetic variation is a major driver of phenotypic diversity, but functional interpretation
is challenging. To better understand common genetic variation associated with brain …
is challenging. To better understand common genetic variation associated with brain …
Ensembl 2005
…, D London, I Longden, G McVicker… - Nucleic acids …, 2005 - academic.oup.com
The Ensembl ( http://www.ensembl.org/ ) project provides a comprehensive and integrated
source of annotation of large genome sequences. Over the last year the number of genomes …
source of annotation of large genome sequences. Over the last year the number of genomes …
WASP: allele-specific software for robust molecular quantitative trait locus discovery
… where G im is the genotype of individual i at test SNP m, and T i is the total number of reads
… Bryce van de Geijn and Graham McVicker: These authors contributed equally to this work. …
… Bryce van de Geijn and Graham McVicker: These authors contributed equally to this work. …
Identification of genetic variants that affect histone modifications in human cells
Histone modifications are important markers of function and chromatin state, yet the DNA
sequence elements that direct them to specific genomic locations are poorly understood. Here, …
sequence elements that direct them to specific genomic locations are poorly understood. Here, …
[HTML][HTML] Widespread genomic signatures of natural selection in hominid evolution
G McVicker, D Gordon, C Davis, P Green - PLoS genetics, 2009 - journals.plos.org
… This column could be the result of a single A→G transition substitution on … →G transitions
on both H and G branches, or an A→G transition on the HCG branch and a back substitution (G…
on both H and G branches, or an A→G transition on the HCG branch and a back substitution (G…
Selective ring opening of naphthenic molecules
GB McVicker, M Daage, MS Touvelle, CW Hudson… - Journal of …, 2002 - Elsevier
Ring opening as practiced in hydrocracking of naphthenic molecules results from multiple
cleavages of both endo- and exocyclic C–C bonds. Selective ring opening requires that only …
cleavages of both endo- and exocyclic C–C bonds. Selective ring opening requires that only …
[HTML][HTML] Controls of nucleosome positioning in the human genome
Nucleosomes are important for gene regulation because their arrangement on the genome
can control which proteins bind to DNA. Currently, few human nucleosomes are thought to …
can control which proteins bind to DNA. Currently, few human nucleosomes are thought to …