R8 development in the Drosophila eye: a paradigm for neural selection and differentiation
BJ Frankfort, G Mardon - 2002 - journals.biologists.com
The Drosophila eye is an outstanding model with which to decipher mechanisms of neural
differentiation. Paramount to normal eye development is the organized selection and …
differentiation. Paramount to normal eye development is the organized selection and …
The sex-determining region of the human Y chromosome encodes a finger protein
…, R Mosher, EM Simpson, EMC Fisher, G Mardon… - cell, 1987 - cell.com
The presence or absence of the Y chromosome determines whether a mammalian embryo
develops as a male or female. In humans, genetic deletion analysis of "sex-reversed" …
develops as a male or female. In humans, genetic deletion analysis of "sex-reversed" …
dachshund encodes a nuclear protein required for normal eye and leg development in Drosophila
G Mardon, NM Solomon, GM Rubin - Development, 1994 - journals.biologists.com
… A side view of a leg disc similar to that in F is shown in G. The arrow in G indicates the portion
of the disc fated to give rise to the distal tarsal segments and claw of the adult leg. Ventral …
of the disc fated to give rise to the distal tarsal segments and claw of the adult leg. Ventral …
Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress
…, P Verstreken, Y Zhou, M Harding, H Bellen, G Mardon - 2004 - journals.biologists.com
Mutations in the gene parkin in humans (PARK2) are responsible for a large number of
familial cases of autosomal-recessive Parkinson disease. We have isolated a Drosophila …
familial cases of autosomal-recessive Parkinson disease. We have isolated a Drosophila …
Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formation
…, R Reshef, RJ Davis, G Mardon, G Oliver… - Genes & …, 1999 - genesdev.cshlp.org
… Moreover, mouse Dach2 (isolated in a screen using the chick Dach2 probe; G. Mardon,
unpubl.) is expressed normally in Pax3 (Splotch; Epstein et al. 1991) mutant mouse embryos (T. …
unpubl.) is expressed normally in Pax3 (Splotch; Epstein et al. 1991) mutant mouse embryos (T. …
[HTML][HTML] Dachshund and eyes absent proteins form a complex and function synergistically to induce ectopic eye development in Drosophila
R Chen, M Amoui, Z Zhang, G Mardon - Cell, 1997 - cell.com
The eyeless, dachshund, and eyes absent genes encode conserved, nuclear proteins that
are essential for eye development in Drosophila. Misexpression of eyeless or dachshund is …
are essential for eye development in Drosophila. Misexpression of eyeless or dachshund is …
The Dachshund gene in development and hormone-responsive tumorigenesis
VM Popov, K Wu, J Zhou, MJ Powell, G Mardon… - Trends in Endocrinology …, 2010 - cell.com
The dachshund (dac) gene was initially described as a mutant phenotype in flies featuring
extremely short legs relative to their body length. Functioning as a dominant suppressor of the …
extremely short legs relative to their body length. Functioning as a dominant suppressor of the …
Eyes absent represents a class of protein tyrosine phosphatases
…, BD Steinmetz, BJ Frankfort, EJ Ostrin, G Mardon… - Nature, 2003 - nature.com
The Eyes absent proteins are members of a conserved regulatory network implicated in the
development of the eye, muscle, kidney and ear 1 , 2 , 3 , 4 , 5 , 6 , 7 . Mutations in the Eyes …
development of the eye, muscle, kidney and ear 1 , 2 , 3 , 4 , 5 , 6 , 7 . Mutations in the Eyes …
Mutations in NMNAT1 cause Leber congenital amaurosis and identify a new disease pathway for retinal degeneration
…, H Jafri, Y Rashid, GR Taylor, V Keser, G Mardon… - Nature …, 2012 - nature.com
Leber congenital amaurosis (LCA) is a blinding retinal disease that presents within the first
year after birth. Using exome sequencing, we identified mutations in the nicotinamide …
year after birth. Using exome sequencing, we identified mutations in the nicotinamide …
Ectopic eye development in Drosophila induced by directed dachshund expression
W Shen, G Mardon - Development, 1997 - journals.biologists.com
The dachshund gene encodes a nuclear protein that is required for normal eye development
in Drosophila. In the absence of dachshund function, flies develop with severely reduced or …
in Drosophila. In the absence of dachshund function, flies develop with severely reduced or …