Nanotechnology-based tools and techniques are rapidly emerging in the fields of medical
imaging and targeted drug delivery. Employing constructs such as dendrimers, liposomes, …

Myocardial ischemia is usually caused by abnormalities of epicardial coronary arteries. In
the past 30 years, however, several studies have shown that abnormalities in coronary …

… VSMC contraction, however, is regulated by a complex, not yet fully elucidated, system of
different intracellular pathways that involve various G proteins, enzymes, and regulatory …

Small noncoding microRNAs (miRNAs) can contribute to cancer development and
progression and are differentially expressed in normal tissues and cancers. From a large-scale …

Noncoding RNA (ncRNA) transcripts are thought to be involved in human tumorigenesis. We
report that a large fraction of genomic ultraconserved regions (UCRs) encode a particular …

… Guido Lanza is Vice President of Biology and co-founder of Pharmix Corporation. He received
his BA degree in 1998 from the University of California at Berkeley from the Department of …

… transcripts containing G or T have different biological functions. We mutated the SNP site
of the retrovirus CCAT2 construct from G to T and transfected HCT116 cells with CCAT2-G or …

… Lanza … Lanza … Drs Lanza and Wickline are cofounders, board members, and equity
holders of Kereos, Inc. RW Fuhrhop and JS Allen are consultants to Kereos, Inc. …

Background Molecular imaging of thrombus within fissures of vulnerable atherosclerotic
plaques requires sensitive detection of a robust thrombus-specific contrast agent. In this study, …

Purpose: Many studies have evaluated the role of high levels of microsatellite instability (MSI)
as a prognostic marker and predictor of the response to chemotherapy in colorectal cancer …