Eleven susceptibility loci for late-onset Alzheimer's disease (LOAD) were identified by previous
studies; however, a large portion of the genetic risk for this disease remains unexplained. …

The Alzheimer Disease Genetics Consortium (ADGC) performed a genome-wide association
study of late-onset Alzheimer disease using a three-stage design consisting of a discovery …

Structural variants are implicated in numerous diseases and make up the majority of varying
nucleotides among human genomes. Here we describe an integrated set of eight structural …

As a first step toward understanding how rare variants contribute to risk for complex diseases,
we sequenced 15,585 human protein-coding genes to an average median depth of 111× …

Establishing the age of each mutation segregating in contemporary human populations is
important to fully understand our evolutionary history 1 , 2 and will help to facilitate the …

The incomplete identification of structural variants (SVs) from whole-genome sequencing
data limits studies of human genetic diversity and disease association. Here, we apply a suite …

The Chinese Tianshan orogenic belt which extends west-east for about 1500 km is one of
the most important Paleozoic orogenic belts in central Asia. It includes parts of the Tarim, Yili-…

… 1350 and 1600 cm –1 , which correspond to the D band and the G band of graphene,
respectively. The I D /I G ratio of the oxidized GOs is ca. 0.99, which decreased to ca. 0.88 in the …

… We assume: y i t P = f ( X i t ) + G i t + θ t P + ε i t P where f(X it ) is a function of observable
variables, X it , G it is the gain from the program accruing to those enrolled in it, θ t P is a period-…

… A thermogravimetric analysis (TGA) was performed using a G 209 F3 at a heating rate of
10 C/min under a N 2 atmosphere. Raman spectra were obtained from 1200 to 3000 cm −1 …