Kidney stones

…, MS Pearle, WG Robertson, G Gambaro… - Nature reviews Disease …, 2016 - nature.com
Kidney stones are mineral deposits in the renal calyces and pelvis that are found free or
attached to the renal papillae. They contain crystalline and organic components and are formed …

Adverse renal effects of anti‐inflammatory agents: evaluation of selective and nonselective cyclooxygenase inhibitors

G Gambaro, MA Perazella - Journal of internal medicine, 2003 - Wiley Online Library
Gambaro G, Perazella MA (Division of Nephrology, University Hospital, Padua, Italy; and
Section of Nephrology, Yale University, New Haven, CT, USA). Adverse renal effects of anti‐…

CKD: a call for an age-adapted definition

…, BO Eriksen, F Gaillard, G Gambaro… - Journal of the …, 2019 - journals.lww.com
Current criteria for the diagnosis of CKD in adults include persistent signs of kidney damage,
such as increased urine albumin-to-creatinine ratio or a GFR below the threshold of 60 ml/…

[HTML][HTML] CKD prevalence varies across the European general population

K Brück, VS Stel, G Gambaro, S Hallan… - Journal of the …, 2016 - journals.lww.com
CKD prevalence estimation is central to CKD management and prevention planning at the
population level. This study estimated CKD prevalence in the European adult general …

[HTML][HTML] Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

…, GA Thun, G Pistis, G Gambaro, G Malerba… - Nature …, 2016 - nature.com
Reduced glomerular filtration rate defines chronic kidney disease and is associated with
cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide …

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

…, SV Eastwood, KU Eckardt, K Fischer, G Gambaro… - Nature …, 2018 - nature.com
We aggregated coding variant data for 81,412 type 2 diabetes cases and 370,832 controls
of diverse ancestry, identifying 40 coding variant association signals (P < 2.2 × 10 −7 ); of …

[PDF][PDF] Urolithiasis

…, K Thomas, G Gambaro… - … at the EAU …, 2022 - docred-strapi-cms-prod.s3.sa-east-1 …
The European Association of Urology (EAU) Urolithiasis Guidelines Panel has prepared these
guidelines to help urologists assess evidence-based management of stones/calculi in the …

[HTML][HTML] Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

…, G Malerba, E Trabetti, HF Zheng, G Gambaro… - Nature …, 2015 - nature.com
Imputing genotypes from reference panels created by whole-genome sequencing (WGS)
provides a cost-effective strategy for augmenting the single-nucleotide polymorphism (SNP) …

A genome-wide association study of anorexia nervosa

…, HE Wichmann, C Dina, R Sladek, G Gambaro… - Molecular …, 2014 - nature.com
Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by
dangerously low body weight. Neither candidate gene studies nor an initial genome-wide …

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

…, P van der Harst, Lifelines Cohort Study, G Gambaro… - Nature …, 2016 - nature.com
High blood pressure is a major risk factor for cardiovascular disease and premature death.
However, there is limited knowledge on specific causal genes and pathways. To better …