The secreted factor netrin‐1 is upregulated in a fraction of human cancers as a mechanism
to block apoptosis induced by netrin‐1 dependence receptors DCC and UNC5H. Targeted …

Single cell transcriptomics is becoming a common technique to unravel new biological
phenomena whose functional significance can only be understood in the light of differences in …

… (g) Violin plots depicting the expression level of genes Correlated or Not-correlated with
the stromal cell content of the tumors, diamond, median value; Expression level (NS=not …

In a number of human cancers, NTN 1 upregulation inhibits apoptosis induced by its so‐called
dependence receptors DCC and UNC 5H, thus promoting tumor progression. In other …

… S1A) characterized by a decreased capacity of Tif1γ −/− -immortalized MEFs to progress
through mitosis as illustrated by their accumulation in G 2 –M phases of the cell cycle (…

… (G) TUNEL assays were performed to label dying cells. After Hoechst staining of the nuclei,
the percentage of TUNEL-positive cells was calculated for each condition and normalized …

Background Gene expression heterogeneity contributes to development as well as disease
progression. Due to technological limitations, most studies to date have focused on …

In embryonic stem (ES) cells, developmental regulators have a characteristic bivalent
chromatin signature marked by simultaneous presence of both activation (H3K4me3) and …

Chronic otitis media with effusion (COME) is the most common cause of childhood hearing
loss in the developed world. Underlying pathophysiology is not well understood, and in …

DNA methylation is thought to induce transcriptional silencing through the combination of
two mechanisms: the repulsion of transcriptional activators unable to bind their target sites …