Neuroprotection mediated through estrogen receptor-α in astrocytes

…, S Du, AJ Wisdom, Y Cao, G Bondar… - Proceedings of the …, 2011 - National Acad Sciences
Estrogen has well-documented neuroprotective effects in a variety of clinical and experimental
disorders of the CNS, including autoimmune inflammation, traumatic injury, stroke, and …

Quinazolinone derivatives as orally available ghrelin receptor antagonists for the treatment of diabetes and obesity

…, DE Bierer, BT Bloomquist, G Bondar… - Journal of medicinal …, 2007 - ACS Publications
… Five hours after compound po administration, a 2 g/kg glucose challenge was administered
by … It was then dried in a vacuum oven at 50 C for 3 h to give 11.5 g (62%) of the product. LC-…

Membrane estrogen receptors stimulate intracellular calcium release and progesterone synthesis in hypothalamic astrocytes

J Kuo, N Hamid, G Bondar, ER Prossnitz… - Journal of …, 2010 - Soc Neuroscience
… Since GPR30 was detected intracellularly but not in the membrane, we interpreted these
results to suggest that G-1 could activate mGluR1a on the membrane and GPR30 on the …

Estradiol-induced estrogen receptor-α trafficking

G Bondar, J Kuo, N Hamid… - Journal of Neuroscience, 2009 - Soc Neuroscience
… ) or 950 μg/ml protein concentration (mouse astrocytes) was incubated with 200 μl of
Immobilized NeutrAvidin Gel (Pierce) for 2 h at room temperature and spun for 1 min at 1000 × g. …

Geometrically non-linear modeling of the Portevin–Le Chatelier effect

T Böhlke, G Bondár, Y Estrin, MA Lebyodkin - Computational materials …, 2009 - Elsevier
… The (implicit) exponential map [44],(23) G p = exp ( Gp G p - 1 Δ t ) G p n fulfils the
incompressibility constraint for G p exactly. Because of the invariance of G p under superimposed …

Membrane estrogen receptor-α interacts with metabotropic glutamate receptor type 1a to mobilize intracellular calcium in hypothalamic astrocytes

J Kuo, OR Hariri, G Bondar, J Ogi, P Micevych - Endocrinology, 2009 - academic.oup.com
G proteins. In neurons, estradiol activates G protein signaling pathways with resulting rapid
action on [Ca 2+ ] i flux (41). However, neuronal mERs do not interact directly with G proteins; …

Leuprorelin acetate every-3-months depot versus cyclophosphamide, methotrexate, and fluorouracil as adjuvant treatment in premenopausal patients with node …

P Schmid, M Untch, V Kossé, G Bondar… - Journal of clinical …, 2007 - ascopubs.org
Purpose Ovarian suppression with luteinizing hormone–releasing hormone (LHRH) agonists
is an effective adjuvant treatment for premenopausal women with estrogen receptor (ER) –…

Protein kinase C signaling in the hypothalamic arcuate nucleus regulates sexual receptivity in female rats

P Dewing, A Christensen, G Bondar… - Endocrinology, 2008 - academic.oup.com
… The antibody-protein complex was absorbed overnight using Protein-G Sepharose 4
Fast Flow with agitation at 4 C (according to the manufacturer protocol). In the morning, the …

[HTML][HTML] Sex differences in hypothalamic astrocyte response to estradiol stimulation

J Kuo, N Hamid, G Bondar, P Dewing, J Clarkson… - Biology of sex …, 2010 - Springer
… Astrocytes were centrifuged for 3 minutes at 80 g, then the supernatant was removed and
the pellet containing astrocytes resuspended. Astrocytes were counted, plated and incubated …

Molecular mechanism of kNBC1–carbonic anhydrase II interaction in proximal tubule cells

…, I Lee, O Fedotoff, G Bondar… - The Journal of …, 2004 - Wiley Online Library
… Approximately 25 g of cells were collected by centrifugation at 6000 g for 20 min, washed …
g for 20 min at 4C. The supernatant was dialysed for 16 h at 4C against PBS, spun at 18 000 g