Cytoscape is open-source software for integration, visualization and analysis of biological
networks. It can be extended through Cytoscape plugins, enabling a broad community of …

Biological Pathway Exchange (BioPAX) is a standard language to represent biological
pathways at the molecular and cellular level and to facilitate the exchange of pathway data. The …

A major goal of proteomics is the complete description of the protein interaction network
underlying cell physiology. A large number of small scale and, more recently, large-scale …

… a We have temporarily removed a group of 352 orphan olfactory GPCRs that previously
were annotated as pre-associated with G-proteins because this reaction mechanism has not …

GeneMANIA ( http://www.genemania.org ) is a flexible, user-friendly web interface for
generating hypotheses about gene function, analyzing gene lists and prioritizing genes for …

A genetic interaction network containing ∼1000 genes and ∼4000 interactions was mapped
by crossing mutations in 132 different query genes into a set of ∼4700 viable gene yeast …

… entire algorithm is polynomial O(nmh 3 ) where n is the number of vertices, m is the number
of edges and h is the vertex size of the average vertex neighbourhood in the input graph, G. …

The availability of human genome sequence has transformed biomedical research over the
past decade. However, an equivalent map for the human proteome with direct …

The autism spectrum disorders (ASDs) are a group of conditions characterized by impairments
in reciprocal social interaction and communication, and the presence of restricted and …

A genome-scale genetic interaction map was constructed by examining 5.4 million gene-gene
pairs for synthetic genetic interactions, generating quantitative genetic interaction profiles …