User profiles for G. K. Aguirre

Geoffrey K Aguirre

Professor of Neurology, University of Pennsylvania
Verified email at upenn.edu
Cited by 22079

Topographical disorientation: a synthesis and taxonomy

GK Aguirre, M D'Esposito - Brain, 1999 - academic.oup.com
Over the last century, several dozen case reports have presented `topographically disoriented'
patients who, in some cases, appear to have selectively lost their ability to find their way …

Event-related functional MRI: implications for cognitive psychology.

M D'Esposito, E Zarahn, GK Aguirre - Psychological bulletin, 1999 - psycnet.apa.org
Functional magnetic resonance imaging (fMRI) has rapidly emerged as a powerful technique
in cognitive neuroscience. We describe and critique a new class of imaging experimental …

Neural components of topographical representation

GK Aguirre, E Zarahn… - Proceedings of the …, 1998 - National Acad Sciences
Studies of patients with focal brain damage suggest that topographical representation is
subserved by dissociable neural subcomponents. This article offers a condensed review of the …

Role of left inferior prefrontal cortex in retrieval of semantic knowledge: a reevaluation

…, M D'Esposito, GK Aguirre… - Proceedings of the …, 1997 - National Acad Sciences
A number of neuroimaging findings have been interpreted as evidence that the left inferior
frontal gyrus (IFG) subserves retrieval of semantic knowledge. We provide a fundamentally …

The variability of human, BOLD hemodynamic responses

GK Aguirre, E Zarahn, M D'Esposito - Neuroimage, 1998 - Elsevier
Cerebral hemodynamic responses to brief periods of neural activity are delayed and dispersed
in time. The specific shape of these responses is of some importance to the design and …

[HTML][HTML] Functional MRI studies of spatial and nonspatial working memory

M d'Esposito, GK Aguirre, E Zarahn, D Ballard… - Cognitive Brain …, 1998 - Elsevier
Single-unit recordings in monkeys have revealed neurons in the lateral prefrontal cortex that
increase their firing during a delay between the presentation of information and its later use …

Empirical analyses of BOLD fMRI statistics

E Zarahn, GK Aguirre, M D'Esposito - Neuroimage, 1997 - Elsevier
Temporal autocorrelation, spatial coherency, and their effects on voxel-wise parametric
statistics were examined in BOLD fMRI null-hypothesis, or “noise,” datasets. Seventeen normal, …

The parahippocampus subserves topographical learning in man

GK Aguirre, JA Detre, DC Alsop, M D'Esposito - Cerebral cortex, 1996 - academic.oup.com
The hippocampus has been proposed as the site of neural representation of large-scale
environmental space, based upon the identification of place cells (neurons with receptive fields …

[HTML][HTML] An area within human ventral cortex sensitive to “building” stimuli: evidence and implications

GK Aguirre, E Zarahn, M D'Esposito - Neuron, 1998 - cell.com
Isolated, ventral brain lesions in humans occasionally produce specific impairments in the
ability to use landmarks, particularly buildings, for way-finding. Using functional MRI, we …

[HTML][HTML] A functional MRI study of mental image generation

M D'Esposito, JA Detre, GK Aguirre, M Stallcup… - Neuropsychologia, 1997 - Elsevier
The neural substrates of mental image generation were investigated with functional MRI.
Subjects listened to words under two different instructional conditions: to generate visual …