A historical perspective of the EGF receptor and related systems

F Edwin, GJ Wiepz, R Singh, CR Peet… - Epidermal Growth Factor …, 2006 - Springer
Since the isolation of epidermal growth factor (EGF) from mouse submaxillary glands in the
early 1950s by Cohen and coworkers, this growth factor has been shown to have various …

[HTML][HTML] Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques

…, B Wolfe, MS Salamat, LBC Teixeira, GJ Wiepz… - PLoS …, 2017 - journals.plos.org
Infection with Zika virus (ZIKV) is associated with human congenital fetal anomalies. To
model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV …

[HTML][HTML] Ocular and uteroplacental pathology in a macaque pregnancy with congenital Zika virus infection

…, X Zeng, AM Weiler, GL Barry, TH Thoong, GJ Wiepz… - PloS one, 2018 - journals.plos.org
Congenital Zika virus (ZIKV) infection impacts fetal development and pregnancy outcomes.
We infected a pregnant rhesus macaque with a Puerto Rican ZIKV isolate in the first trimester…

Evidence for nucleotide receptor modulation of cross talk between MAP kinase and NF-κB signaling pathways in murine RAW 264.7 macrophages

…, JJ Watters, ZA Pfeiffer, GJ Wiepz… - … of physiology-cell …, 2004 - journals.physiology.org
Extracellular nucleotides such as ATP are present in abundance at sites of inflammation
and tissue damage, and these agents exert a potent modulatory effect on macrophage/…

[HTML][HTML] In Vitro CRISPR/Cas9-Directed Gene Editing to Model LRRK2 G2019S Parkinson's Disease in Common Marmosets

…, S To, S Guthrie, JH Kluss, JK Schmidt, GJ Wiepz… - Scientific reports, 2020 - nature.com
Leucine-rich repeat kinase 2 (LRRK2) G2019S is a relatively common mutation, associated
with 1–3% of Parkinson’s disease (PD) cases worldwide. G2019S is hypothesized to …

[HTML][HTML] Epidermal growth factor-stimulated tyrosine phosphorylation of caveolin-1: enhanced caveolin-1 tyrosine phosphorylation following aberrant epidermal …

YN Kim, GJ Wiepz, AG Guadarrama… - Journal of Biological …, 2000 - ASBMB
Caveolin-1 is the major coat protein of caveolae and has been reported to interact with various
intracellular signaling molecules including the epidermal growth factor (EGF) receptor. To …

Using liquid crystals to report membrane proteins captured by affinity microcontact printing from cell lysates and membrane extracts

CH Jang, ML Tingey, NL Korpi, GJ Wiepz… - Journal of the …, 2005 - ACS Publications
The chemical heterogeneity of proteins makes development of general and facile surface-based
methods for protein analysis a substantial challenge, particularly when analyzing …

Acute Fetal Demise with First Trimester Maternal Infection Resulting from Listeria monocytogenes in a Nonhuman Primate Model

B Wolfe, GJ Wiepz, M Schotzko, GI Bondarenko… - MBio, 2017 - Am Soc Microbiol
Infection with Listeria monocytogenes during pregnancy is associated with miscarriage,
preterm birth, and neonatal complications, including sepsis and meningitis. While the risk of …

Effects of norgestomet, altrenogest, and/or estradiol on follicular and hormonal characteristics of late transitional mares

GJ Wiepz, EL Squires, PL Chapman - Theriogenology, 1988 - Elsevier
Two experiments were conducted to investigate the effect of norgestomet and altrenogest,
alone or in combination with estradiol, on late transitional mares. In the first experiment, 32 …

[HTML][HTML] Integrin-mediated migration of murine B82L fibroblasts is dependent on the expression of an intact epidermal growth factor receptor

J Li, ML Lin, GJ Wiepz, AG Guadarrama… - Journal of Biological …, 1999 - ASBMB
To evaluate the mechanisms by which epidermal growth factor (EGF) regulates actin-based
cellular processes such as cell migration, we first examined the effects of EGF on cell …