Aging is a major risk factor for many neurological diseases and is associated with mild
cognitive decline. Previous studies suggest that aging is accompanied by reduced synapse …

… Little is known about exactly what MICALs interact with except an affinity for the cytoskeleton
[57]. However, MICALs have clearly been implicated in class3 semaphorin signalling, which …

To what extent, how and when axons respond to injury in the highly interconnected grey
matter is poorly understood. Here we use two-photon imaging and focused ion beam–scanning …

Background The trajectory of corticospinal tract (CST) axons from cortex to spinal cord involves
a succession of choice points, each of which is controlled by multiple guidance molecules…

The establishment of connectivity between specific thalamic nuclei and cortical areas involves
a dynamic interplay between the guidance of thalamocortical axons and the elaboration of …

Psychiatric disorders such as schizophrenia and autism are characterised by cellular
disorganisation and dysconnectivity across the brain and can be caused by mutations in genes that …

Background Sensory processing relies on projections from the thalamus to the neocortex
being established during development. Information from different sensory modalities reaching …

Problems with joint attention (JA) are core features of Autism Spectrum Disorders (ASD).
Here, we investigate how typically developing (TD) children and children with ASD respond to …

… Professor Tesón's point may be well taken, but there should be little objection in adopting
various approaches from various schools of feminism, especially early on in the process of …

Atherosclerosis is the immuno-metabolic disease involving chronic inflammation, oxidative
stress, epigenetics, and metabolic dysfunction. There is compelling evidence suggesting …