User profiles for G. A. Cary

Gregory A Cary, PhD

Bioinformatics Analyst, The Jackson Laboratory
Verified email at jax.org
Cited by 581

[HTML][HTML] Echinoderm development and evolution in the post-genomic era

GA Cary, VF Hinman - Developmental biology, 2017 - Elsevier
The highly recognizable animals within the phylum Echinodermata encompass an
enormous disparity of adult and larval body plans. The extensive knowledge of sea urchin …

Echinobase: leveraging an extant model organism database to build a knowledgebase supporting research on the genomics and biology of echinoderms

BI Arshinoff, GA Cary, K Karimi, S Foley… - Nucleic acids …, 2022 - academic.oup.com
Echinobase ( www.echinobase.org ) is a third generation web resource supporting genomic
research on echinoderms. The new version was built by cloning the mature Xenopus model …

[HTML][HTML] Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development

GA Cary, BS McCauley, O Zueva, J Pattinato… - Nature …, 2020 - nature.com
The extensive array of morphological diversity among animal taxa represents the product of
millions of years of evolution. Morphology is the output of development, therefore phenotypic …

[HTML][HTML] Analysis of sea star larval regeneration reveals conserved processes of whole-body regeneration across the metazoa

GA Cary, A Wolff, O Zueva, J Pattinato, VF Hinman - BMC biology, 2019 - Springer
Background Metazoan lineages exhibit a wide range of regenerative capabilities that vary
among developmental stage and tissue type. The most robust regenerative abilities are …

EchinoBase: tools for echinoderm genome analyses

GA Cary, RA Cameron, VF Hinman - Eukaryotic Genomic Databases …, 2018 - Springer
The echinoderms are a phylum of invertebrate deuterostome animals that constitute
important research models for a number of biological disciplines. EchinoBase ( www.echinobase.…

The effect of suspended solids and naturally occurring dissolved organics in reducing the acute toxicities of cationic polyelectrolytes to aquatic organisms

GA Cary, JA McMahon, WJ Kuc - Environmental Toxicology and …, 1987 - Wiley Online Library
Cationic polyelectrolytes comprise a large group of chemicals designed to react with and
flocculate suspended solids. Their primary use is as water clarification aids in the removal of …

Androgen receptor function in motor neuron survival and degeneration

GA Cary, AR La Spada - Physical medicine and rehabilitation clinics of …, 2008 - Elsevier
Polyglutamine repeat expansion in the androgen receptor is responsible for the motor neuron
degeneration in X-linked spinal and bulbar muscular atrophy (SBMA; Kennedy's disease). …

Genomic resources for the study of echinoderm development and evolution

GA Cary, RA Cameron, VF Hinman - Methods in Cell Biology, 2019 - Elsevier
Echinoderms are important research models for a wide range of biological questions. In
particular, echinoderm embryos are exemplary models for dissecting the molecular and cellular …

[HTML][HTML] Developmental transcriptomes of the sea star, Patiria miniata, illuminate how gene expression changes with evolutionary distance

T Gildor, GA Cary, M Lalzar, VF Hinman… - Scientific reports, 2019 - nature.com
Understanding how changes in developmental gene expression alter morphogenesis is a
fundamental problem in development and evolution. A promising approach to address this …

Genome-wide use of high-and low-affinity Tbrain transcription factor binding sites during echinoderm development

GA Cary, AM Cheatle Jarvela… - Proceedings of the …, 2017 - National Acad Sciences
Sea stars and sea urchins are model systems for interrogating the types of deep evolutionary
changes that have restructured developmental gene regulatory networks (GRNs). Although …