User profiles for F. Tanaka

Fumihide Tanaka

Professor, University of Tsukuba
Verified email at iit.tsukuba.ac.jp
Cited by 4144

Enamine-based organocatalysis with proline and diamines: the development of direct catalytic asymmetric aldol, Mannich, Michael, and Diels− Alder reactions

W Notz, F Tanaka, CF Barbas - Accounts of chemical research, 2004 - ACS Publications
Enamines and imines have long been recognized as key intermediates in enzyme catalysis,
particularly within a class of enzymes organic chemists would very much like to emulate, the …

Social robots for education: A review

…, A Ramachandran, B Scassellati, F Tanaka - Science robotics, 2018 - science.org
Social robots can be used in education as tutors or peer learners. They have been shown to
be effective at increasing cognitive and affective outcomes and have achieved outcomes …

[HTML][HTML] Recurrence after surgery in patients with NSCLC

H Uramoto, F Tanaka - Translational lung cancer research, 2014 - ncbi.nlm.nih.gov
Surgery remains the only potentially curative modality for early-stage non-small cell lung
cancer (NSCLC) patients and tissue availability is made possible. However, a proportion of …

[HTML][HTML] Neoadjuvant nivolumab plus chemotherapy in resectable lung cancer

…, TE Ciuleanu, GB Saylors, F Tanaka… - … England Journal of …, 2022 - Mass Medical Soc
Background Neoadjuvant or adjuvant chemotherapy confers a modest benefit over surgery
alone for resectable non–small-cell lung cancer (NSCLC). In early-phase trials, nivolumab-…

De novo computational design of retro-aldol enzymes

…, A Zanghellini, JL Gallaher, JL Betker, F Tanaka… - science, 2008 - science.org
The creation of enzymes capable of catalyzing any desired chemical reaction is a grand
challenge for computational protein design. Using new algorithms that rely on hashing …

The Encyclopedia of DNA elements (ENCODE): data portal update

…, JS Strattan, O Jolanki, FY Tanaka… - Nucleic acids …, 2018 - academic.oup.com
… In 2003, the NHGRI formed the Encyclopedia of DNA Elements (ENCODE) project with
the aim of bringing together a variety of experimental and computational labs to identify …

Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers

…, K Mimori, K Kawahara, S Imoto, T Sudo, F Tanaka… - Cancer research, 2011 - AACR
The functional impact of recently discovered long noncoding RNAs (ncRNAs) in human
cancer remains to be clarified. One long ncRNA which has attracted attention is the Hox …

Viscoelastic properties of physically crosslinked networks. 1. Transient network theory

F Tanaka, SF Edwards - Macromolecules, 1992 - ACS Publications
A simple model is introduced to describe the dynamics of physically cross-linked networks
in which junctions are sufficiently weak to break and recombine in thermal fluctuations. The …

Organocatalytic direct asymmetric aldol reactions in water

…, N Ohara, H Yoda, K Takabe, F Tanaka… - Journal of the …, 2006 - ACS Publications
We have developed direct asymmetric cross-aldol reactions that can be performed in water
without addition of organic solvents. A bifunctional catalyst with a long hydrophobic alkyl …

Characterization of a side population of cancer cells from human gastrointestinal system

N Haraguchi, T Utsunomiya, H Inoue, F Tanaka… - Stem …, 2006 - academic.oup.com
A subset of stem cells, termed “side population” (SP) cells, has been identified and
characterized in several mammalian tissues and cell lines. However, SP cells have never been …