… Out of 100 treated patients (88 M, 12 F; median age: 62 years), 43 received TCZ in the
intensive care unit (ICU), while 57 in the general ward as no ICU beds were available. Of these 57 …

Here we discuss recent advances in understanding the biochemical, immunologic, and genetic
pathogenesis of IgA nephropathy, the most common primary glomerulonephritis. Current …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as coronavirus
disease (COVID-19), is a major pandemic challenging health care systems around the …

Background Stratum 2 of the Ramipril Efficacy in Nephropathy (REIN) study has already
shown that in patients with chronic nephropathies and proteinuria of 3 g or more per 24 h, …

We carried out a genome-wide association study of IgA nephropathy, a major cause of kidney
failure worldwide. We studied 1,194 cases and 902 controls of Chinese Han ancestry, with …

The outcome of SARS-CoV2 infection in patients who have received a kidney allograft and
are being treated with immunosuppression is unclear. We describe 20 kidney transplant …

We performed a genome-wide association study (GWAS) of IgA nephropathy (IgAN), the most
common form of glomerulonephritis, with discovery and follow-up in 20,612 individuals of …

To assess whether chlorambucil or cyclophosphamide may have a better therapeutic index
in patients with idiopathic membranous nephropathy, we compared two regimens based on …

End-stage renal disease (ESRD) is a major public health problem, affecting 1 in 1,000 individuals
and with an annual death rate of 20% despite dialysis treatment 1, 2. IgA nephropathy (…

IgA nephropathy (IgAN), major cause of kidney failure worldwide, is common in Asians,
moderately prevalent in Europeans, and rare in Africans. It is not known if these differences …