[HTML][HTML] Heritable transgene-free genome editing in plants by grafting of wild-type shoots to transgenic donor rootstocks
Generation of stable gene-edited plant lines using clustered regularly interspaced short
palindromic repeats (CRISPR)–CRISPR-associated protein 9 (Cas9) requires a lengthy process …
palindromic repeats (CRISPR)–CRISPR-associated protein 9 (Cas9) requires a lengthy process …
[HTML][HTML] Nucleolar and ribosomal DNA structure under stress: yeast lessons for aging and cancer
E Matos-Perdomo, F Machín - Cells, 2019 - mdpi.com
Once thought a mere ribosome factory, the nucleolus has been viewed in recent years as
an extremely sensitive gauge of diverse cellular stresses. Emerging concepts in nucleolar …
an extremely sensitive gauge of diverse cellular stresses. Emerging concepts in nucleolar …
SMC5 and SMC6 genes are required for the segregation of repetitive chromosome regions
J Torres-Rosell, F Machín, S Farmer, A Jarmuz… - Nature cell …, 2005 - nature.com
Abstract Structure chromosome (SMC) proteins organize the core of cohesin, condensin and
Smc5–Smc6 complexes 1 . The Smc5–Smc6 complex is required for DNA repair, as well as …
Smc5–Smc6 complexes 1 . The Smc5–Smc6 complex is required for DNA repair, as well as …
Smc5–Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination
DNA double-strand breaks (DSB) can arise during DNA replication, or after exposure to
DNA-damaging agents, and their correct repair is fundamental for cell survival and genomic …
DNA-damaging agents, and their correct repair is fundamental for cell survival and genomic …
The Canary Eddy Corridor: A major pathway for long-lived eddies in the subtropical North Atlantic
We report, from remote sensing and in situ observations, a new type of permanent structure
in the eastern subtropical Atlantic Ocean, that we call the “Canary Eddy Corridor”. The …
in the eastern subtropical Atlantic Ocean, that we call the “Canary Eddy Corridor”. The …
Cdc14 inhibits transcription by RNA polymerase I during anaphase
Chromosome condensation and the global repression of gene transcription 1 are features
of mitosis in most eukaryotes. The logic behind this phenomenon is that chromosome …
of mitosis in most eukaryotes. The logic behind this phenomenon is that chromosome …
Imaging meddy finestructure using multichannel seismic reflection data
This work illustrates the great potential of multichannel seismic reflection data to extract
information from the finestructure of meddies with exceptional lateral resolution (10–15 m). We …
information from the finestructure of meddies with exceptional lateral resolution (10–15 m). We …
Anaphase onset before complete DNA replication with intact checkpoint responses
…, V Cordon-Preciado, S Farmer, A Jarmuz, F Machin… - Science, 2007 - science.org
Cellular checkpoints prevent mitosis in the presence of stalled replication forks. Whether
checkpoints also ensure the completion of DNA replication before mitosis is unknown. Here, we …
checkpoints also ensure the completion of DNA replication before mitosis is unknown. Here, we …
Mass fluxes in the Canary Basin
Ocean studies in the 1970s provided an improved knowledge of the coastal upwelling
region off NW Africa while in the 1980s and 1990s they led to a good description of the open …
region off NW Africa while in the 1980s and 1990s they led to a good description of the open …
Shoot and root single cell sequencing reveals tissue-and daytime-specific transcriptome profiles
Although several large-scale single-cell RNA sequencing (scRNAseq) studies addressing
the root of Arabidopsis (Arabidopsis thaliana) have been published, there is still need for a de …
the root of Arabidopsis (Arabidopsis thaliana) have been published, there is still need for a de …