User profiles for F. Luciani

Fabio Luciani

Professor, University of New South Wales, Sydney, Australia
Verified email at unsw.edu.au
Cited by 6935

SARS-CoV-2 and COVID-19: A genetic, epidemiological, and evolutionary perspective

…, SE Hasnain, B Rosenthal, T Phan, F Luciani… - Infection, genetics and …, 2020 - Elsevier
In less than five months, COVID-19 has spread from a small focus in Wuhan, China, to more
than 5 million people in almost every country in the world, dominating the concern of most …

[HTML][HTML] Inhibitors of the hepatitis C virus polymerase; mode of action and resistance

AA Eltahla, F Luciani, PA White, AR Lloyd, RA Bull - Viruses, 2015 - mdpi.com
The hepatitis C virus (HCV) is a pandemic human pathogen posing a substantial health and
economic burden in both developing and developed countries. Controlling the spread of …

[HTML][HTML] COVID-19 vaccines: current and future perspectives

…, C Pulvirenti, A Cozza, A Corsonello, F Luciani… - Vaccines, 2022 - mdpi.com
Currently available vaccines against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
are highly effective but not able to keep the coronavirus disease 2019 (COVID-19) …

Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs

F Luciani, M Spada, A De Milito… - Journal of the …, 2004 - academic.oup.com
… Uptake phase: panels A , B , E , and F show melanoma cells after a 6-hour incubation with
F. Luciani and L. Lugini were supported by a fellowship from Fondazione Italiana per la …

Immune surveillance properties of human NK cell-derived exosomes

…, V Huber, F Luciani, G Macchia, F Spadaro… - The Journal of …, 2012 - journals.aai.org
Exosomes are nanovesicles released by normal and tumor cells, which are detectable in cell
culture supernatant and human biological fluids, such as plasma. Functions of exosomes …

[HTML][HTML] Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state

…, V Christiaens, D Svetlichnyy, F Luciani… - Nature …, 2015 - nature.com
Transcriptional reprogramming of proliferative melanoma cells into a phenotypically distinct
invasive cell subpopulation is a critical event at the origin of metastatic spreading. Here we …

β-Catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development

…, L Denat, J Goodall, F Luciani… - Genes & …, 2007 - genesdev.cshlp.org
… Immunostaining for tyrosinase (E) and Tyrp-1 (F) in an amelanotic melanoma was revealed
… (F) Increasing amounts of bcat sta inhibit endogenous p16 INK4a mRNA expression in …

MDM4 is a key therapeutic target in cutaneous melanoma

A Gembarska, F Luciani, C Fedele, EA Russell… - Nature medicine, 2012 - nature.com
… (e,f) RT-qPCR mRNA expression analysis of selected p53 target genes in the MM031 (e)
and MM011 (f) melanoma cell lines 24 h after treatment. The data represent the means ± sd …

VDJdb: a curated database of T-cell receptor sequences with known antigen specificity

…, EB Clemens, DC Douek, F Luciani… - Nucleic acids …, 2018 - academic.oup.com
The ability to decode antigen specificities encapsulated in the sequences of rearranged T-cell
receptor (TCR) genes is critical for our understanding of the adaptive immune system and …

[HTML][HTML] Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysis

…, A Verich, H Gamaarachchi, KW Kim, F Luciani… - Nature …, 2020 - nature.com
Viral whole-genome sequencing (WGS) provides critical insight into the transmission and
evolution of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Long-read …