The use of molecular genetics in the improvement of agricultural populations

JCM Dekkers, F Hospital - Nature Reviews Genetics, 2002 - nature.com
Substantial advances have been made in the genetic improvement of agriculturally important
animal and plant populations through artificial selection on quantitative traits. Most of this …

[HTML][HTML] Current controversies in the management of aortoiliac occlusive disease

DC Brewster, FMG Hospital, HM School - Journal of vascular surgery, 1997 - Elsevier
… in Sweden, immediate and 1-year results of PTA and surgery were equivalent, and patients
who underwent PTA had a significantly shorter hospital stay. It is important to note, however, …

[HTML][HTML] Assessing the impact of transgenerational epigenetic variation on complex traits

…, D Bouchez, C Dillmann, P Guerche, F Hospital… - PLoS …, 2009 - journals.plos.org
Loss or gain of DNA methylation can affect gene expression and is sometimes transmitted
across generations. Such epigenetic alterations are thus a possible source of heritable …

Mapping the epigenetic basis of complex traits

…, E Caillieux, F Hospital, JM Aury, P Wincker, F Roudier… - Science, 2014 - science.org
Quantifying the impact of heritable epigenetic variation on complex traits is an emerging
challenge in population genetics. Here, we analyze a population of isogenic Arabidopsis lines …

Selection in backcross programmes

F Hospital - … Transactions of the Royal Society B …, 2005 - royalsocietypublishing.org
Hospital, F. 2001 Size of donor chromosome segments around introgressed loci and
reduction of linkage drag in marker-assisted backcross programs. Genetics 158, 1363–1379. …

Toward a theory of marker-assisted gene pyramiding

B Servin, OC Martin, M Mézard, F Hospital - Genetics, 2004 - academic.oup.com
… . Suppose an intermediate genotype H is to be obtained from the cross of two (nonfounding)
parents H m and H f . Rather than cross H m and H f directly, we first cross each separately …

Marker-assisted introgression of quantitative trait loci

F Hospital, A Charcosset - Genetics, 1997 - academic.oup.com
… on background selection efficiency was investigated by HOSPITAL et al. (1992, Tables 1 and
2 … Conversely, the efficiency on carrier chromosomes in Table '7 is lower than in HOSPITAL

Using markers in gene introgression breeding programs.

F Hospital, C Chevalet, P Mulsant - Genetics, 1992 - academic.oup.com
We investigate the use of markers to hasten the recovery of the recipient genome during an
introgression breeding program. The effects of time and intensity of selection, population size…

Selective sweep at a quantitative trait locus in the presence of background genetic variation

LM Chevin, F Hospital - Genetics, 2008 - academic.oup.com
We model selection at a locus affecting a quantitative trait (QTL) in the presence of genetic
variance due to other loci. The dynamics at the QTL are related to the initial genotypic value …

Genome-wide epigenetic perturbation jump-starts patterns of heritable variation found in nature

…, F Hospital, V Colot, RC Jansen, F Johannes - Genetics, 2011 - academic.oup.com
We extensively phenotyped 6000 Arabidopsis plants with experimentally perturbed DNA
methylomes as well as a diverse panel of natural accessions in a common garden. We found …