User profiles for F. Gambon-Deza

Francisco Gambon Deza

Immunologist, Hospital do Meixoeiro
Verified email at sergas.es
Cited by 1263

Presence of an unique IgT on the IGH locus in three-spined stickleback fish (Gasterosteus aculeatus) and the very recent generation of a repertoire of VH genes

F Gambón-Deza, C Sánchez-Espinel… - Developmental & …, 2010 - Elsevier
This study describes the IGH locus in Gasterosteus aculeatus, with 10 genes encoding three
immunoglobulin classes: IgT, IgM and IgD. These genes are organized into a structure with …

Insights into the evolution of IG genes in amphibians and reptiles

…, S Mirete-Bachiller, F Gambón-Deza - Developmental & …, 2021 - Elsevier
Immunoglobulins are essential proteins of the immune system to neutralize pathogens. Gene
encoding B cell receptors and antibodies (Ig genes) first appeared with the emergence of …

[HTML][HTML] Immunoglobulin heavy chains in medaka (Oryzias latipes)

…, C Sánchez-Espinel, F Gambón-Deza - BMC evolutionary …, 2011 - Springer
Background Bony fish present an immunological system, which evolved independently from
those of animals that migrated to land 400 million years ago. The publication of whole …

IgD in the reptile leopard gecko

F Gambón-Deza, CS Espinel - Molecular immunology, 2008 - Elsevier
Immunoglobulin D (IgD) has been a mysterious antibody ever since it was discovered in
mammals 40 years ago. It shares with IgM the role of antigen-receptor in the membrane of …

IgH loci of American alligator and saltwater crocodile shed light on IgA evolution

…, C Sánchez-Espinel, F Gambón-Deza - Immunogenetics, 2013 - Springer
Immunoglobulin loci of two representatives of the order Crocodylia were studied from full
genome sequences. Both Alligator mississippiensis and Crocodylus porosus have 13 genes for …

The immunoglobulin heavy chain locus in the platypus (Ornithorhynchus anatinus)

F Gambón-Deza, C Sánchez-Espinel… - Molecular …, 2009 - Elsevier
… carolinensis (Gambon-Deza, 2009), we described the existence of numerous families with
few members, wherein indicated the possibility of grouping such families into 5 groups. The …

[HTML][HTML] From IgZ to IgT: A call for a common nomenclature for immunoglobulin heavy chain genes of ray-finned fish

…, Z Xu, MF Flajnik, A Singer, F Gambón-Deza… - Zebrafish, 2021 - liebertpub.com
Ray-finned fishes comprise more than half the* 60,000 known vertebrate species, 1 and are
pivotal to the functionality of aquatic ecosystems and success of global multibillion dollar …

Lymphocyte populations during tuberculosis infection: V beta repertoires

F Gambón-Deza, M Pacheco Carracedo… - Infection and …, 1995 - Am Soc Microbiol
The immune response to Mycobacterium tuberculosis is mediated by T lymphocytes. We
studied the changes in lymphocyte populations occurring in peripheral blood, pleural fluid, and …

Snakes antibodies

F Gambón-Deza, C Sánchez-Espinel… - Developmental & …, 2012 - Elsevier
Immunoglobulins are basic molecules of the immune system of vertebrates. In previous
studies we described the immunoglobulins found in two squamata reptiles, Anolis carolinensis …

An automated algorithm for extracting functional immunologic V-genes from genomes in jawed vertebrates

…, B von Haeften, C Sánchez-Espinel, F Gambón-Deza - Immunogenetics, 2013 - Springer
Variable (V) domains of immunoglobulins (Ig) and T cell receptors (TCR) are generated from
genomic V gene segments (V-genes). At present, such V-genes have been annotated only …