[PDF][PDF] Gradients of Rac1 nanoclusters support spatial patterns of Rac1 signaling

A Remorino, S De Beco, F Cayrac, F Di Federico… - Cell reports, 2017 - cell.com
Rac1 is a small RhoGTPase switch that orchestrates actin branching in space and time and
protrusion/retraction cycles of the lamellipodia at the cell front during mesenchymal migration…

[HTML][HTML] Optogenetic dissection of Rac1 and Cdc42 gradient shaping

…, K Vaidžiulytė, J Manzi, F Dalier, F Di Federico… - Nature …, 2018 - nature.com
During cell migration, Rho GTPases spontaneously form spatial gradients that define the
front and back of cells. At the front, active Cdc42 forms a steep gradient whereas active Rac1 …

Microfluidic extraction and digital quantification of circulating cell-free DNA from serum

…, I Pereiro, S Garrigou, F Di Federico… - Sensors and Actuators B …, 2019 - Elsevier
Miniaturized devices for the extraction of DNA have been used for assessing genetic material
in biological, forensic and environmental samples. However, the ability to isolate trace …

Forces drive basement membrane invasion in Caenorhabditis elegans

…, J Dreier, J Manzi, F Di Federico… - Proceedings of the …, 2018 - National Acad Sciences
… To understand the effect of activator deletion on actin dynamics in the AC, we imaged F-actin
in the AC over time during WT and WSP-1/N-WASP-deleted AC invasion, which occurred …

[HTML][HTML] Predictive biomarkers for checkpoint inhibitor-based immunotherapy in hepatocellular carcinoma: where do we stand?

A Rizzo, AD Ricci, A Di Federico, G Frega… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) remains the sixth most commonly diagnosed malignancy
worldwide, still representing an important cause of cancer-related death. Over the next few …

Skin cancer triage and management during COVID‐19 pandemic

…, L Del Regno, S Gentileschi, F Federico… - Journal of the …, 2020 - Wiley Online Library
Di Stefani … Di Stefani has nothing to disclose. Dr. Schinzari has nothing to disclose. …
Federico has nothing to disclose. Dr. Valentini has nothing to disclose. …

Beyond EGFR, ALK and ROS1: current evidence and future perspectives on newly targetable oncogenic drivers in lung adenocarcinoma

…, A Rizzo, C Parisi, A Di Federico, F Gelsomino… - Critical reviews in …, 2020 - Elsevier
Lung cancer is the leading cause of cancer death worldwide. In the past decade EGFR, ALK
and ROS1 TKIs lead to an unprecedented survival improvement of oncogene-addicted …

Outward FDI and local employment growth in Italy

S Federico, GA Minerva - Review of World Economics, 2008 - Springer
… Our main result is that, controlling for the local industrial structure and area fixed effects, FDI
… higher levels of FDI. Our findings do not support therefore the idea that FDI is detrimental to …

Alvin Langdon Coburn and the Genesis of Vortographs

F DiFederico - History of photography, 1987 - Taylor & Francis
… back in Boston, he showed a portfolio of his prints to F. Holland Day, a distant cousin, who
was sufficiently impressed with the young man's pictures that he took on Coburn as a protege …

[HTML][HTML] The biggest business process management problems to solve before we die

…, T Chen, I Cohen, B Depaire, G Di Federico… - Computers in …, 2023 - Elsevier
… Reijers a , Stefanie Rinderle-Ma c , Wasana Bandara d , Andrea Burattin e , Diego
Calvanese f , Tianwa Chen g , Izack Cohen h , Benoît Depaire v , Gemma Di Federico e , Marlon …