User profiles for F. Chiaromonte

Francesca Chiaromonte

Professor of Statistics, Pennsylvania State University, Sant'Anna School of Advanced …
Verified email at psu.edu
Cited by 22569

[HTML][HTML] Complete Khoisan and Bantu genomes from southern Africa

…, ER Mardis, N Patterson, TH Pringle, F Chiaromonte… - Nature, 2010 - nature.com
The genetic structure of the indigenous hunter-gatherer peoples of southern Africa, the oldest
known lineage of modern human, is important for understanding human diversity. Studies …

Scoring pairwise genomic sequence alignments

F Chiaromonte, VB Yap, W Miller - Biocomputing 2002, 2001 - World Scientific
The parameters by which alignments are scored can strongly affect sensitivity and specificity
of alignment procedures. While appropriate parameter choices are well understood for …

Evidence for sharp increase in the economic damages of extreme natural disasters

…, F Lamperti, K Keller, F Chiaromonte… - Proceedings of the …, 2019 - National Acad Sciences
Climate change has increased the frequency and intensity of natural disasters. Does this
translate into increased economic damages? To date, empirical assessments of damage trends …

Contour regression: a general approach to dimension reduction

B Li, H Zha, F Chiaromonte - 2005 - projecteuclid.org
… in a typical location regression of the form Y = f (X) + ε with X and ε independent and both
normally distributed, this assumption is not met unless f(·) is linear. Because of its generality, …

[HTML][HTML] Qualitative network models and genome-wide expression data define carbon/nitrogen-responsive molecular machines in Arabidopsis

RA Gutiérrez, LV Lejay, A Dean, F Chiaromonte… - Genome biology, 2007 - Springer
Background Carbon (C) and nitrogen (N) metabolites can regulate gene expression in
Arabidopsis thaliana. Here, we use multinetwork analysis of microarray data to identify molecular …

The genome-wide determinants of human and chimpanzee microsatellite evolution

YD Kelkar, S Tyekucheva, F Chiaromonte… - Genome …, 2008 - genome.cshlp.org
Mutation rates of microsatellites vary greatly among loci. The causes of this heterogeneity
remain largely enigmatic yet are crucial for understanding numerous human neurological …

Covariation in frequencies of substitution, deletion, transposition, and recombination during eutherian evolution

…, N Goldman, A Smit, W Miller, F Chiaromonte… - Genome …, 2003 - genome.cshlp.org
Six measures of evolutionary change in the human genome were studied, three derived
from the aligned human and mouse genomes in conjunction with the Mouse Genome …

Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression

…, SC Schuster, W Miller, F Chiaromonte… - Genome …, 2009 - genome.cshlp.org
The transcription factor GATA1 regulates an extensive program of gene activation and
repression during erythroid development. However, the associated mechanisms, including the …

Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA

…, TS Korneliussen, F Chiaromonte… - Proceedings of the …, 2014 - National Acad Sciences
The manifestation of mitochondrial DNA (mtDNA) diseases depends on the frequency of
heteroplasmy (the presence of several alleles in an individual), yet its transmission across …

Envelope models for parsimonious and efficient multivariate linear regression

RD Cook, B Li, F Chiaromonte - Statistica Sinica, 2010 - JSTOR
… A basis matrix f subspace S is any matrix whose columns form a basis for S. A semi-ortho …
The particular method proposed by Cook, Li and Chiaromonte (2007) is a first step along these …