Since its original description 50 years ago, myocardial ischemia has been a recognized but
underappreciated aspect of the pathophysiology of hypertrophic cardiomyopathy (HCM). …

… Inferolateral Q waves are evident on the ECG (F). AML indicates anterior mitral leaflet; FT, …
End-systolic CMR images (E and F) show preserved systolic function causing cavity …

Introduction: Under normal conditions, hepatocyte growth factor (HGF)-induced activation of
its cell surface receptor, the Met tyrosine kinase (TK), is tightly regulated by paracrine ligand …

In biology, classification systems are used to promote understanding and systematic discussion
through the use of logical groups and hierarchies. In clinical medicine, similar principles …

Background The influence of left ventricular outflow tract obstruction on the clinical outcome
of hypertrophic cardiomyopathy remains unresolved. Methods We assessed the effect of …

Background— Hypertrophic cardiomyopathy (HCM) is the most common cause of sudden
death in the young, although not all patients eligible for sudden death prevention with an …

Background— Nonobstructive hypertrophic cardiomyopathy (HCM) has been regarded as
the predominant hemodynamic form of the disease on the basis of assessment of outflow …

Background—Death resulting from hypertrophic cardiomyopathy (HCM), particularly when
sudden, has been reported to be largely confined to young persons. These data emanated …

Background Clinical impact of atrial fibrillation (AF) in hypertrophic cardiomyopathy (HCM)
is largely unresolved. Thus, we analyzed the prognostic implications of AF in a large, …

Background Microvascular dysfunction, reflected by an inadequate increase in myocardial
blood flow in response to dipyridamole infusion, is a recognized feature of hypertrophic …