User profiles for F. Canzian

Federico Canzian

Group Leader, German Cancer Research Center (DKFZ)
Verified email at dkfz.de
Cited by 32294

[HTML][HTML] The PANcreatic Disease ReseArch (PANDoRA) consortium: Ten years' experience of association studies to understand the genetic architecture of pancreatic …

…, L Archibugi, M Lucchesi, C Rizzato, F Canzian - Critical reviews in …, 2023 - Elsevier
Pancreatic cancer has an incidence that almost matches its mortality. Only a small number of
risk factors and 33 susceptibility loci have been identified. so Moreover, the relative rarity of …

Germline genetic variability in pancreatic cancer risk and prognosis

…, F Canzian, A Nicolini, F Gemignani… - Seminars in cancer …, 2022 - Elsevier
Pancreatic cancer (PC), particularly its most common form, pancreatic ductal adenocarcinoma
(PDAC), is relatively rare but highly lethal. Knowledge about PC risk factors could in the …

Polymorphisms affecting micro-RNA regulation and associated with the risk of dietary-related cancers: a review from the literature and new evidence for a functional …

…, A Naccarati, F Canzian, R Barale, F Gemignani… - Mutation Research …, 2011 - Elsevier
In this review, we focus on the genetic variations (single nucleotide polymorphisms, SNPs)
known to occur in microRNAs and in their binding sites and the susceptibility to cancers of the …

Association analysis identifies 65 new breast cancer risk loci

…, K Butterbach, Q Cai, H Cai, T Caldés, F Canzian… - Nature, 2017 - nature.com
Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as
BRCA1, and many common, mostly non-coding variants. However, much of the genetic …

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

…, G Andriole, J Schleutker, M Weischer, F Canzian… - Nature …, 2013 - nature.com
Prostate cancer is the most frequently diagnosed cancer in males in developed countries.
To identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a …

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

…, NBCS, GG Giles, RL Milne, C McLean, F Canzian… - Nature …, 2015 - nature.com
Genome-wide association studies (GWAS) and large-scale replication studies have identified
common variants in 79 loci associated with breast cancer, explaining ∼14% of the familial …

Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer

…, JE Buring, PM Bracci, F Canzian, F Clavel-Chapelon… - Nature …, 2009 - nature.com
We conducted a two-stage genome-wide association study of pancreatic cancer, a cancer
with one of the lowest survival rates worldwide. We genotyped 558,542 SNPs in 1,896 …

Association between telomere length and risk of cancer and non-neoplastic diseases: a Mendelian randomization study

…, NC Onland-Moret, E Lund, EJ Duell, F Canzian… - JAMA …, 2017 - jamanetwork.com
Importance The causal direction and magnitude of the association between telomere length
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

…, J Donovan, RC Travis, TJ Key, A Siddiq, F Canzian… - Nature …, 2014 - nature.com
Genome-wide association studies (GWAS) have identified 76 variants associated with
prostate cancer risk predominantly in populations of European ancestry. To identify additional …

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci

…, D Trichopoulos, N Caporaso, MT Landi, F Canzian… - Nature …, 2010 - nature.com
We conducted a multi-stage, genome-wide association study of bladder cancer with a
primary scan of 591,637 SNPs in 3,532 affected individuals (cases) and 5,120 controls of …