User profiles for F. Barthel
Floris P BarthelThe Translational Genomics Research Institute (TGen) Verified email at tgen.org Cited by 6822 |
Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future …
…, BM Alexander, JS Barnholtz-Sloan, FP Barthel… - Neuro …, 2020 - academic.oup.com
Glioblastomas are the most common form of malignant primary brain tumor and an important
cause of morbidity and mortality. In recent years there have been important advances in …
cause of morbidity and mortality. In recent years there have been important advances in …
[PDF][PDF] Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma
Therapy development for adult diffuse glioma is hindered by incomplete knowledge of somatic
glioma driving alterations and suboptimal disease classification. We defined the complete …
glioma driving alterations and suboptimal disease classification. We defined the complete …
[PDF][PDF] Tumor evolution of glioma-intrinsic gene expression subtypes associates with immunological changes in the microenvironment
…, AC DeCarvalho, S Lyu, P Li, Y Li, F Barthel… - Cancer cell, 2017 - cell.com
We leveraged IDH wild-type glioblastomas, derivative neurospheres, and single-cell gene
expression profiles to define three tumor-intrinsic transcriptional subtypes designated as …
expression profiles to define three tumor-intrinsic transcriptional subtypes designated as …
Comprehensive and integrated genomic characterization of adult soft tissue sarcomas
…, S Sadeghi, FP Barthel, R Verhaak, X Hu, F Chibon… - Cell, 2017 - discovery.ucl.ac.uk
Sarcomas are a broad family of mesenchymal malignancies exhibiting remarkable histologic
diversity. We describe the multi-platform molecular landscape of 206 adult soft tissue …
diversity. We describe the multi-platform molecular landscape of 206 adult soft tissue …
[PDF][PDF] Glioma progression is shaped by genetic evolution and microenvironment interactions
The factors driving therapy resistance in diffuse glioma remain poorly understood. To
identify treatment-associated cellular and genetic changes, we analyzed RNA and/or DNA …
identify treatment-associated cellular and genetic changes, we analyzed RNA and/or DNA …
[HTML][HTML] Reconstructing the molecular life history of gliomas
FP Barthel, P Wesseling, RGW Verhaak - Acta neuropathologica, 2018 - Springer
At the time of their clinical manifestation, the heterogeneous group of adult and pediatric
gliomas carries a wide range of diverse somatic genomic alterations, ranging from somatic …
gliomas carries a wide range of diverse somatic genomic alterations, ranging from somatic …
Longitudinal molecular trajectories of diffuse glioma in adults
The evolutionary processes that drive universal therapeutic resistance in adult patients with
diffuse glioma remain unclear 1 , 2 . Here we analysed temporally separated DNA-…
diffuse glioma remain unclear 1 , 2 . Here we analysed temporally separated DNA-…
Systematic analysis of telomere length and somatic alterations in 31 cancer types
Cancer cells survive cellular crisis through telomere maintenance mechanisms. We report
telomere lengths in 18,430 samples, including tumors and non-neoplastic samples, across 31 …
telomere lengths in 18,430 samples, including tumors and non-neoplastic samples, across 31 …
Normalizing economic loss from natural disasters: A global analysis
E Neumayer, F Barthel - Global Environmental Change, 2011 - Elsevier
… 5(a–f) we therefore look at developed vis-à-vis developing countries as well as at specific
regions of the world, employing the same list of weather-related disasters as in Fig. 4. Looking …
regions of the world, employing the same list of weather-related disasters as in Fig. 4. Looking …
Transport buyers choice of transport service–A literature review of empirical results
J Flodén, F Bärthel, E Sorkina - Research in Transportation Business & …, 2017 - Elsevier
Highlights • Price is most important when choosing transport services. • Quality related factors
are also of high importance. • Environmental impact is given very low importance. • There …
are also of high importance. • Environmental impact is given very low importance. • There …