[PDF][PDF] Extensive unexplored human microbiome diversity revealed by over 150,000 genomes from metagenomes spanning age, geography, and lifestyle

…, F Asnicar, S Manara, M Zolfo, N Karcher, F Armanini… - Cell, 2019 - cell.com
The body-wide human microbiome plays a role in health, but its full diversity remains
uncharacterized, particularly outside of the gut and in international populations. We leveraged …

[PDF][PDF] Mother-to-infant microbial transmission from different body sites shapes the developing infant gut microbiome

…, A Tett, F Asnicar, V Gorfer, S Fedi, F Armanini… - Cell host & …, 2018 - cell.com
The acquisition and development of the infant microbiome are key to establishing a healthy
host-microbiome symbiosis. The maternal microbial reservoir is thought to play a crucial role …

[HTML][HTML] The person-to-person transmission landscape of the gut and oral microbiomes

…, F Asnicar, L Dubois, D Golzato, F Armanini, F Cumbo… - Nature, 2023 - nature.com
The human microbiome is an integral component of the human body and a co-determinant of
several health conditions 1 , 2 . However, the extent to which interpersonal relations shape …

[HTML][HTML] Cross-cohort gut microbiome associations with immune checkpoint inhibitor response in advanced melanoma

…, JR Björk, LK de Ruijter, F Armanini, F Asnicar… - Nature medicine, 2022 - nature.com
The composition of the gut microbiome has been associated with clinical responses to
immune checkpoint inhibitor (ICI) treatment, but there is limited consensus on the specific …

Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation

…, F Asnicar, E Pasolli, F Armanini, M Zolfo, F Beghini… - Nature medicine, 2019 - nature.com
… Analysis of Composition of Microbes was also applied 68 , but showed reduced power
on our datasets (for example, it identified F. nucleatum as a biomarker in only one dataset) …

Fecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

…, M Ninkov, G Piccinno, F Armanini, F Pinto… - Nature medicine, 2023 - nature.com
Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance
to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of …

[HTML][HTML] Variability of strain engraftment and predictability of microbiome composition after fecal microbiota transplantation across different diseases

…, S Porcari, F Armanini, F Asnicar, F Beghini… - Nature Medicine, 2022 - nature.com
Fecal microbiota transplantation (FMT) is highly effective against recurrent Clostridioides
difficile infection and is considered a promising treatment for other microbiome-related disorders…

[PDF][PDF] The Prevotella copri complex comprises four distinct clades underrepresented in westernized populations

…, H Fehlner-Peach, E Pasolli, N Karcher, F Armanini… - Cell host & …, 2019 - cell.com
Prevotella copri is a common human gut microbe that has been both positively and
negatively associated with host health. In a cross-continent meta-analysis exploiting >6,500 …

Improved sampling and DNA extraction procedures for microbiome analysis in food-processing environments

…, F Armanini, N Carlino, A Blanco-Míguez, F Pinto… - Nature …, 2024 - nature.com
Deep investigation of the microbiome of food-production and food-processing environments
through whole-metagenome sequencing (WMS) can provide detailed information on the …

Studying vertical microbiome transmission from mothers to infants by strain-level metagenomic profiling

…, S Manara, M Zolfo, DT Truong, M Scholz, F Armanini… - …, 2017 - Am Soc Microbiol
The gut microbiome becomes shaped in the first days of life and continues to increase its
diversity during the first months. Links between the configuration of the infant gut microbiome …