User profiles for F. S. Collins

Frank Collins

UW
Verified email at uw.edu
Cited by 28925

Finding the missing heritability of complex diseases

TA Manolio, FS Collins, NJ Cox, DB Goldstein… - Nature, 2009 - nature.com
Genome-wide association studies have identified hundreds of genetic variants associated
with complex human diseases and traits, and have provided valuable insights into their …

Mutations in the p53 gene occur in diverse human tumour types

…, N Davidson, S Baylin, P Devilee, T Glover, FS Collins… - Nature, 1989 - nature.com
THE p53 gene has been a constant source of fascination since its discovery nearly a decade
ago 1,2 . Originally considered to be an oncogene, several convergent lines of research …

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

…, JL Chou, ML Drumm, MC Iannuzzi, FS Collins… - Science, 1989 - science.org
Overlapping complementary DNA clones were isolated from epithelial cell libraries with a
genomic DNA segment containing a portion of the putative cystic fibrosis (CF) locus, which is …

[HTML][HTML] A new initiative on precision medicine

FS Collins, H Varmus - New England journal of medicine, 2015 - Mass Medical Soc
President Obama has announced a research initiative that aims to accelerate progress
toward a new era of precision medicine, with a near-term focus on cancers and a longer …

The Human Genome Project: lessons from large-scale biology

FS Collins, M Morgan, A Patrinos - Science, 2003 - science.org
… We each joined the ranks of HGP management during the challenging period of the early
to mid-1990s, with Francis Collins assuming the lead role at the NIH in 1993, Michael Morgan …

New goals for the US human genome project: 1998-2003

FS Collins, A Patrinos, E Jordan, A Chakravarti… - science, 1998 - science.org
FS Collins and E. Jordan are with the National Human Genome Research Institute, National
FS Collins and E. Jordan are with the National Human Genome Research Institute, National …

Cystic ibrosis: Molecular Biology and Therapeutic Implications

FS Collins - Science, 1992 - science.org
… Wilson, and members of the Collins, Wilson, and Dawson CF research groups at the University
of Michigan. Supported by a Cystic Fibrosis Foundation Research Development Program …

[BOOK][B] The language of God: A scientist presents evidence for belief

FS Collins - 2006 - books.google.com
… “Francis Collins has written an extraordinary personal testimony about the compatibility of
God … Collins shows how our understanding of evolution, far from standing in the way of faith, …

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

…, L Castilla, M Swaroop, K Blanchard, FS Collins… - Cell, 1993 - cell.com
The Huntington's disease (HD) gene has been mapped in 4p16.3 but has eluded identification.
We have used haplotype analysis of linkage disequilibrium to spotlight a small segment …

The international HapMap project

…, K Todani, T Fujita, S Tanaka, AL Holden, FS Collins… - 2003 - deepblue.lib.umich.edu
The goal of the International HapMap Project is to determine the common patterns of DNA
sequence variation in the human genome and to make this information freely available in the …