High-quality datasets are needed to understand how global and local properties of protein-protein
interaction, or 'interactome', networks relate to biological mechanisms, and to guide …

In both special education and speech-language pathology literature, it is commonly assumed
that children's reading difficulties have their roots in early oral language disabilities. Data …

Although introns in 5′‐ and 3′‐untranslated regions (UTRs) are found in many protein
coding genes, rarely are they considered distinctive entities with specific functions. Indeed, …

Systematic mapping of protein–protein interactions, or ‘interactome’ mapping, was initiated
in model organisms, starting with defined biological processes 1 , 2 and then expanding to …

A genetic interaction network containing ∼1000 genes and ∼4000 interactions was mapped
by crossing mutations in 132 different query genes into a set of ∼4700 viable gene yeast …

A genome-scale genetic interaction map was constructed by examining 5.4 million gene-gene
pairs for synthetic genetic interactions, generating quantitative genetic interaction profiles …

To initiate studies on how protein-protein interaction (or “interactome”) networks relate to
multicellular functions, we have mapped a large fraction of the Caenorhabditis elegans …

In apparently scale-free protein–protein interaction networks, or ‘interactome’ networks 1 , 2
, most proteins interact with few partners, whereas a small but significant proportion of …

Current yeast interactome network maps contain several hundred molecular complexes with
limited and somewhat controversial representation of direct binary interactions. We carried …

The ability to perturb genes in human cells is crucial for elucidating gene function and holds
great potential for finding therapeutic targets for diseases such as cancer. To extend the …