[HTML][HTML] The Discovery, Distribution, and Evolution of Viruses Associated with Drosophila melanogaster
CL Webster, FM Waldron, S Robertson, D Crowson… - PLoS …, 2015 - journals.plos.org
Drosophila melanogaster is a valuable invertebrate model for viral infection and antiviral
immunity, and is a focus for studies of insect-virus coevolution. Here we use a metagenomic …
immunity, and is a focus for studies of insect-virus coevolution. Here we use a metagenomic …
[HTML][HTML] Metagenomic sequencing suggests a diversity of RNA interference-like responses to viruses across multicellular eukaryotes
RNA interference (RNAi)-related pathways target viruses and transposable element (TE)
transcripts in plants, fungi, and ecdysozoans (nematodes and arthropods), giving protection …
transcripts in plants, fungi, and ecdysozoans (nematodes and arthropods), giving protection …
Targeting mitochondrial dysfunction in amyotrophic lateral sclerosis: a systematic review and meta-analysis
Interventions targeting mitochondrial dysfunction have the potential to extend survival in
preclinical models of amyotrophic lateral sclerosis. The aim of this systematic review was to …
preclinical models of amyotrophic lateral sclerosis. The aim of this systematic review was to …
The virome of Drosophila suzukii, an invasive pest of soft fruit
Drosophila suzukii (Matsumura) is one of the most damaging and costly pests to invade
temperate horticultural regions in recent history. Conventional control of this pest is challenging, …
temperate horticultural regions in recent history. Conventional control of this pest is challenging, …
Systematic, comprehensive, evidence-based approach to identify neuroprotective interventions for motor neuron disease: using systematic reviews to inform expert …
…, T Soane, A Thompson, O Tomala, FM Waldron… - BMJ open, 2023 - bmjopen.bmj.com
Objectives Motor neuron disease (MND) is an incurable progressive neurodegenerative
disease with limited treatment options. There is a pressing need for innovation in identifying …
disease with limited treatment options. There is a pressing need for innovation in identifying …
[HTML][HTML] RNA aptamer reveals nuclear TDP-43 pathology is an early aggregation event that coincides with STMN-2 cryptic splicing and precedes clinical …
TDP-43 is an aggregation-prone protein which accumulates in the hallmark pathological
inclusions of amyotrophic lateral sclerosis (ALS). However, the analysis of deeply phenotyped …
inclusions of amyotrophic lateral sclerosis (ALS). However, the analysis of deeply phenotyped …
pTDP‐43 aggregates accumulate in non‐central nervous system tissues prior to symptom onset in amyotrophic lateral sclerosis: a case series linking archival surgical …
…, MJ Arends, MH Horrocks, FM Waldron… - The Journal of …, 2023 - Wiley Online Library
Neurodegenerative diseases such as Parkinson's disease (PD), Alzheimer's disease (AD),
and amyotrophic lateral sclerosis (ALS) are traditionally considered strictly neurological …
and amyotrophic lateral sclerosis (ALS) are traditionally considered strictly neurological …
Respiratory responses to air-exposure in the southern rock lobster, Jasus edwardsii (Hutton)(Decapoda: Palinuridae)
HH Taylor, FM Waldron - Marine and Freshwater Research, 1997 - CSIRO Publishing
Air-exposure of settled Jasus edwardsii at 17C initially halved oxygen consumption, doubled
ventilation frequency and reduced heart rate. During 8 h emersion, oxygen uptake partially …
ventilation frequency and reduced heart rate. During 8 h emersion, oxygen uptake partially …
Distinct neuroinflammatory signatures exist across genetic and sporadic amyotrophic lateral sclerosis cohorts
…, AF Munro, MDE Sewell, S Abrahams, FM Waldron… - Brain, 2023 - academic.oup.com
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by
progressive loss of upper and lower motor neurons. ALS is on a pathogenetic disease spectrum …
progressive loss of upper and lower motor neurons. ALS is on a pathogenetic disease spectrum …
Testing evolutionary explanations for the lifespan benefit of dietary restriction in fruit flies (Drosophila melanogaster)
E Savola, C Montgomery, FM Waldron, KM Monteith… - …, 2021 - academic.oup.com
Dietary restriction (DR), limiting calories or specific nutrients without malnutrition, extends
lifespan across diverse taxa. Traditionally, this lifespan extension has been explained as a …
lifespan across diverse taxa. Traditionally, this lifespan extension has been explained as a …