… /Cas9 cell lines; HZ and FM performed ASO treatments in SMA mice; PB, TT, EP, EJNG, …
FM is a principal investigator on an Ionis-funded clinical trial on AON in SMA and in a Roche…

Spinal muscular atrophy (SMA) is a neuromuscular disease caused by low levels of SMN
protein, primarily affecting lower motor neurons. Recent evidence from SMA and related …

What does it mean to be a man? How do men see themselves in relation to other men, to
women, and to both the feminine and the masculine aspects of their own selves? In this …

The model of Drosophila female meiosis I was recently revised by the discovery that chromosome
congression precedes metaphase I arrest. Use of the prior framework to interpret data …

Prion diseases are enigmatic, neurodegenerative disorders affecting several mammalian
species. The family of diseases include scrapie of sheep, bovine spongiform encephalopathy (…

The β2–α2 loop of PrP C is a key modulator of disease-associated prion protein misfolding.
Amino acids that differentiate mouse (Ser169, Asn173) and deer (Asn169, Thr173) PrP C …

One essential role of the first meiotic division is to reduce chromosome number by half.
Although this is normally accomplished by segregating homologous chromosomes from each …

… Their naive application implies the leading asymptotic behavior G (p)∼(ln p)− A, where A is
… , with the effective coupling g 2 (p)∼(ln p)− 1, when the strong interactions are asymptotically …

… had FM, but most of those with FM (… FM a generalized disorder, and there is less evidence
of distress in those with TMD. TMD is a separate disorder from FM, but many patients with FM …

Recently, researchers have focused on a group of children and youth who are at high risk
for developing a lifelong pernicious pattern of antisocial and delinquent behavior.These …