Prostate cancer is a common malignancy in men and the worldwide burden of this disease is
rising. Lifestyle modifications such as smoking cessation, exercise, and weight control offer …

CONTEXT: MicroRNAs (miRNA) are noncoding RNAs that post-transcriptionally regulate
gene expression. Their altered expression and function have been observed in most urologic …

OBJECTIVE:: Measurement of serum prostate-specific antigen (PSA) for the detection of
prostate cancer has poor specificity in men with PSA levels between 2 and 10ng/ml. It has been …

Background The comparative effectiveness of treatments for prostate cancer that is detected
by prostate-specific antigen (PSA) testing remains uncertain. Methods We compared active …

… Hamdy can be contacted at freddie . hamdy@ nds . ox . ac . … Hamdy and Bryant are
supported by the Oxford NIHR Biomedical Research Centre, Surgical Innovation and Evaluation …

Background Robust data on patient-reported outcome measures comparing treatments for
clinically localized prostate cancer are lacking. We investigated the effects of active monitoring…

Prostate cancer is the most common cancer affecting males in developed countries. It shows
consistent evidence of familial aggregation, but the causes of this aggregation are mostly …

Background: The aim of this study was to investigate the hypothesis that changes in circulating
microRNAs (miRs) represent potentially useful biomarkers for the diagnosis, staging and …

Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified
more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data …

Prostate cancer is the most frequently diagnosed cancer in males in developed countries.
To identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a …