User profiles for E. Westhof

Eric Westhof

Architecture et Réactivité de l'ARN Université de Strasbourg Institut de biologie
Verified email at unistra.fr
Cited by 48287

Halogen bonds in biological molecules

P Auffinger, FA Hays, E Westhof… - Proceedings of the …, 2004 - National Acad Sciences
Short oxygen–halogen interactions have been known in organic chemistry since the 1950s
and recently have been exploited in the design of supramolecular assemblies. The present …

Hierarchy and dynamics of RNA folding

P Brion, E Westhof - Annual review of biophysics and …, 1997 - annualreviews.org
▪ Abstract The evidence showing that the self-assembly of complex RNAs occurs in discrete
transitions, each relating to the folding of sub-systems of increasing size and complexity …

The building blocks and motifs of RNA architecture

NB Leontis, A Lescoute, E Westhof - Current opinion in structural biology, 2006 - Elsevier
… The structures are annotated for base-pairing interactions using the geometric nomenclature
of Leontis and Westhof [31]. (b) Superposition of the canonical helices (C helix) from the 3D …

Genome evolution in yeasts

…, F Tekaia, M Wésolowski-Louvel, E Westhof… - Nature, 2004 - nature.com
… Arrays are defined as a succession of genes encoding paralogous proteins (as defined by
protein families and with a BLASTP E-value <10 -20 ) allowing a maximum of ten intervening …

Geometric nomenclature and classification of RNA base pairs

NB Leontis, E Westhof - Rna, 2001 - cambridge.org
… structures, as recently reviewed (Leontis & Westhof, 1998c)+ They often result from an open…
insertion of one water molecule (see, e+g+, Fig+ 3 of Westhof & Fritsch, 2000)+ We propose …

Modelling of the three-dimensional architecture of group I catalytic introns based on comparative sequence analysis

F Michel, E Westhof - Journal of molecular biology, 1990 - Elsevier
… The P2 and P9 terminal loops are shown in full detail, together with the G residues in stems
P8 and P5, respectively, with which they interact (not,e that we did not model the interaction …

[HTML][HTML] Single processing center models for human Dicer and bacterial RNase III

H Zhang, FA Kolb, L Jaskiewicz, E Westhof… - Cell, 2004 - cell.com
Dicer is a multidomain ribonuclease that processes double-stranded RNAs (dsRNAs) to 21
nt small interfering RNAs (siRNAs) during RNA interference, and excises microRNAs from …

The non‐Watson–Crick base pairs and their associated isostericity matrices

NB Leontis, J Stombaugh, E Westhof - Nucleic acids research, 2002 - academic.oup.com
… In fact, I 1 and I 2 are mutually compatible, thus U/A and C/A are observed to co‐vary in the
loop E motifs of 5S rRNA and SRP ( 2 , 32 ). U/G is placed in its own group (I 3 ) because it is …

[PDF][PDF] A standard reference frame for the description of nucleic acid base-pair geometry

…, H Sklenar, M Suzuki, CS Tung, E Westhof… - Journal of molecular …, 2001 - academia.edu
A common point of reference is needed to describe the three-dimensional arrangements of
bases and base-pairs in nucleic acid structures. The different standards used in computer …

Correlation between segmental mobility and the location of antigenic determinants in proteins

E Westhof, D Altschuh, D Moras, AC Bloomer… - Nature, 1984 - nature.com
Most continuous antigenic determinants of tobacco mosaic virus protein (TMVP), myoglobin
and lysozyme correspond to those surface regions in the protein structure, as determined by …