User profiles for E. Pierson

Elizabeth Pierson

- Verified email at tamu.edu - Cited by 8463

Emma Pierson

- Verified email at cornell.edu - Cited by 8206

Targeting virulence: a new paradigm for antimicrobial therapy

AE Clatworthy, E Pierson, DT Hung - Nature chemical biology, 2007 - nature.com
Clinically significant antibiotic resistance has evolved against virtually every antibiotic
deployed. Yet the development of new classes of antibiotics has lagged far behind our growing …

[HTML][HTML] Metabolism and function of phenazines in bacteria: impacts on the behavior of bacteria in the environment and biotechnological processes

LS Pierson, EA Pierson - Applied microbiology and biotechnology, 2010 - Springer
Phenazines constitute a large group of nitrogen-containing heterocyclic compounds
produced by a diverse range of bacteria. Both natural and synthetic phenazine derivatives are …

Ethical machine learning in healthcare

IY Chen, E Pierson, S Rose, S Joshi… - Annual review of …, 2021 - annualreviews.org
The use of machine learning (ML) in healthcare raises numerous ethical concerns, especially
as models can amplify existing health inequities. Here, we outline ethical considerations …

[HTML][HTML] Mobility network models of COVID-19 explain inequities and inform reopening

S Chang, E Pierson, PW Koh, J Gerardin, B Redbird… - Nature, 2021 - nature.com
The coronavirus disease 2019 (COVID-19) pandemic markedly changed human mobility
patterns, necessitating epidemiological models that can capture the effects of these changes in …

Wilds: A benchmark of in-the-wild distribution shifts

…, J Leskovec, A Kundaje, E Pierson… - International …, 2021 - proceedings.mlr.press
Distribution shifts—where the training distribution differs from the test distribution—can
substantially degrade the accuracy of machine learning (ML) systems deployed in the wild. …

Algorithmic decision making and the cost of fairness

S Corbett-Davies, E Pierson, A Feller, S Goel… - Proceedings of the 23rd …, 2017 - dl.acm.org
Algorithms are now regularly used to decide whether defendants awaiting trial are too
dangerous to be released back into the community. In some cases, black defendants are …

Concept bottleneck models

…, YS Tang, S Mussmann, E Pierson… - International …, 2020 - proceedings.mlr.press
We seek to learn models that we can interact with using high-level concepts: if the model
did not think there was a bone spur in the x-ray, would it still predict severe arthritis? State-of-the…

[HTML][HTML] Complete genome sequence of the plant commensal Pseudomonas fluorescens Pf-5

…, K Tran, H Khouri, EA Pierson, LS Pierson III… - Nature …, 2005 - nature.com
Pseudomonas fluorescens Pf-5 is a plant commensal bacterium that inhabits the rhizosphere
and produces secondary metabolites that suppress soilborne plant pathogens. The …

[HTML][HTML] Comparative Genomics of Plant-Associated Pseudomonas spp.: Insights into Diversity and Inheritance of Traits Involved in Multitrophic Interactions

…, AJ Anderson, YC Kim, LS Pierson III, EA Pierson… - PLoS …, 2012 - journals.plos.org
We provide here a comparative genome analysis of ten strains within the Pseudomonas
fluorescens group including seven new genomic sequences. These strains exhibit a diverse …

[HTML][HTML] ZIFA: Dimensionality reduction for zero-inflated single-cell gene expression analysis

E Pierson, C Yau - Genome biology, 2015 - Springer
… Computing the value of the parameters at each iteration requires two steps: the expectation
step (E-step) and the maximization step (M-step). In the E-step, we derive an expression for …