… It is made up of a protein complex containing the known ZA components E-cadherin, α- and
β-catenin (Armadillo, Arm), and the protein Discs lost (Dlt), which contains four PDZ domains…

The evolutionarily conserved Crumbs protein complex is a key regulator of cell polarity and
cell shape in both invertebrates and vertebrates. The important role of this complex in normal …

… (E) Electron microscopic section at the level of the OLM showing AJs between photoreceptor
and Müller glia cells. (F) Schematic illustration of the AJs and SAR, where the CRB/Crb …

We describe the molecular characterization of the Drosophila gene crumbs, which encodes
an integral membrane protein with 30 EGF-like repeats in the extracellular part and exhibits …

… One of the proteins that is of crucial importance for the establishment of cell polarity in the
early mouse embryo is the homophilic cell adhesion molecule uvomorulin (E-cadherin). Mouse …

… c–e, Baz staining is reduced in neuroblasts of insc mutants. c, In heterozygous insc P49 /CyO
blue embryos, Baz is detectable in the apical region of the neuroectodermal epithelium (…

The establishment and maintenance of polarity is of fundamental importance for the function
of epithelial and neuronal cells. In Drosophila, the multi-PDZ domain protein Bazooka (Baz) …

… 1d, e). To further assay that the cloned gene corresponded to sdt, we carried out rescue
experiments. GAL4-mediated overexpression of UAS-cGUK1 did not rescue the sdt loss-of-…

… The E. coli cells are schematically represented with a dotted circle. With the first two steps
the ‘pre-tagging’ cassette is inserted, which is replaced in the next three steps with the sGFP …

… (e,f) Frontal views of dissected CNS preparations of stage 13 (e) AJ96/AJ96 and (f)
baz815–8/Y; AJ96/+ embryos stained with anti β-galactosidase antibody (blue) and 22C10 (brown), …