The mitotic spindle: a self-made machine
E Karsenti, I Vernos - Science, 2001 - science.org
The mitotic spindle is a highly dynamic molecular machine composed of tubulin, motors,
and other molecules. It assembles around the chromosomes and distributes the duplicated …
and other molecules. It assembles around the chromosomes and distributes the duplicated …
Self-organization in cell biology: a brief history
E Karsenti - Nature reviews Molecular cell biology, 2008 - nature.com
Over the past two decades, molecular and cell biologists have made important progress in
characterizing the components and compartments of the cell. New visualization methods …
characterizing the components and compartments of the cell. New visualization methods …
Tara Oceans: towards global ocean ecosystems biology
A planetary-scale understanding of the ocean ecosystem, particularly in light of climate
change, is crucial. Here, we review the work of Tara Oceans, an international, multidisciplinary …
change, is crucial. Here, we review the work of Tara Oceans, an international, multidisciplinary …
Structure and function of the global ocean microbiome
Microbes are dominant drivers of biogeochemical processes, yet drawing a global picture of
functional diversity, microbial community structure, and their ecological determinants …
functional diversity, microbial community structure, and their ecological determinants …
Eukaryotic plankton diversity in the sunlit ocean
…, J Weissenbach, P Wincker, E Karsenti, E Boss… - Science, 2015 - science.org
Marine plankton support global biological and geochemical processes. Surveys of their
biodiversity have hitherto been geographically restricted and have not accounted for the full …
biodiversity have hitherto been geographically restricted and have not accounted for the full …
Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts
Functional nuclei and mitotic spindles are shown to assemble around DNA-coated beads
incubated in Xenopus egg extracts. Bipolar spindles assemble in the absence of centrosomes …
incubated in Xenopus egg extracts. Bipolar spindles assemble in the absence of centrosomes …
Determinants of community structure in the global plankton interactome
Species interaction networks are shaped by abiotic and biotic factors. Here, as part of the
Tara Oceans project, we studied the photic zone interactome using environmental factors and …
Tara Oceans project, we studied the photic zone interactome using environmental factors and …
[HTML][HTML] Ran induces spindle assembly by reversing the inhibitory effect of importin α on TPX2 activity
…, J Kast, M Wilm, N Le Bot, I Vernos, E Karsenti… - Cell, 2001 - cell.com
The small GTPase Ran, bound to GTP, is required for the induction of spindle formation by
chromosomes in M phase. High concentrations of Ran.GTP are proposed to surround M …
chromosomes in M phase. High concentrations of Ran.GTP are proposed to surround M …
Plankton networks driving carbon export in the oligotrophic ocean
The biological carbon pump is the process by which CO 2 is transformed to organic carbon
via photosynthesis, exported through sinking particles, and finally sequestered in the deep …
via photosynthesis, exported through sinking particles, and finally sequestered in the deep …
Phosphorylation and activation of human cdc25‐C by cdc2‐‐cyclin B and its involvement in the self‐amplification of MPF at mitosis.
I Hoffmann, PR Clarke, MJ Marcote, E Karsenti… - The EMBO …, 1993 - embopress.org
… Draetta and E.Karsenti, in preparation). We assessed the ability of exogenous cdc25-C to
activate the cdc2-cyclin Bi complex in these extracts by measuring the cdc2 histone HI kinase …
activate the cdc2-cyclin Bi complex in these extracts by measuring the cdc2 histone HI kinase …