… Author links open overlay panel Eero Kajantie a b c , David IW Phillips b … ), although in
elderly women this correlation appears to be weaker (Kajantie et al., 2004). It is of note that the …

Background Small birth size may be associated with increased risk of cardiovascular diseases
(CVD), whereas large birth size may predict increased risk of obesity and some cancers. …

… from studies in Helsinki and elsewhere suggest that set-points for non-HDL cholesterol
metabolism are established in response to fetal nutrition and liver growth in utero (Kajantie et al. …

Most common human traits and diseases have a polygenic pattern of inheritance: DNA
sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA…

Waist-hip ratio (WHR) is a measure of body fat distribution and a predictor of metabolic
consequences independent of overall adiposity. WHR is heritable, but few genetic variants …

Very few genetic variants have been associated with depression and neuroticism, likely
because of limitations on sample size in previous studies. Subjective well-being, a phenotype …

Background Low birth weight is a risk factor for coronary heart disease. It is uncertain how
postnatal growth affects disease risk. Methods We studied 8760 people born in Helsinki from …

Background The association between small size at birth and impaired glucose regulation later
in life is well established in persons born at term. Preterm birth with very low birth weight (<…

OBJECTIVE Proinsulin is a precursor of mature insulin and C-peptide. Higher circulating
proinsulin levels are associated with impaired β-cell function, raised glucose levels, insulin …

The growth of every human fetus is constrained by the limited capacity of the mother and
placenta to deliver nutrients to it. At birth, boys tend to be longer than girls at any placental …