Antioxidant potential of ferulic acid

E Graf - Free radical biology and medicine, 1992 - Elsevier
Ferulic acid is a ubiquitous plant constituent that arises from the metabolism of phenylalanine
and tyrosine. It occurs primarily in seeds and leaves both in its free form and covalently …

Antioxidant functions of phytic acid

E Graf, JW Eaton - Free Radical Biology and Medicine, 1990 - Elsevier
… acid have been extensively reviewed in a prior monograph. ~2 X-ray crystallographic
analyses of … Graf, E.; Dintzis, FR HPLC method for the determination of phytate. Anal. Biochem. …

Pharmacology of synthetic organic selenium compounds

MJ Parnham, E Graf, VM Kolb, R Seth, S Sinha… - Progress in Drug …, 1991 - Springer
The similarity in the chemical properties of sulfur and selenium has tempted medical
chemists for many years to prepare, for comparative purposes, a wide variety of selenium …

Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study

A Rauch, D Wieczorek, E Graf, T Wieland, S Endele… - The Lancet, 2012 - thelancet.com
Background The genetic cause of intellectual disability in most patients is unclear because
of the absence of morphological clues, information about the position of such genes, and …

[PDF][PDF] A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease

A Zimprich, A Benet-Pagès, W Struhal, E Graf… - The American Journal of …, 2011 - cell.com
To identify rare causal variants in late-onset Parkinson disease (PD), we investigated an
Austrian family with 16 affected individuals by exome sequencing. We found a missense …

High-density miniaturized thermal shift assays as a general strategy for drug discovery

…, J Myslik, E Graf, T Carver, E Asel… - Journal of …, 2001 - journals.sagepub.com
More general and universally applicable drug discovery assay technologies are needed in
order to keep pace with the recent advances in combinatorial chemistry and genomics-based …

[HTML][HTML] Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins

ER Graf, XZ Zhang, SX Jin, MW Linhoff, AM Craig - Cell, 2004 - cell.com
Formation of synaptic connections requires alignment of neurotransmitter receptors on
postsynaptic dendrites opposite matching transmitter release sites on presynaptic axons. β-…

Hemoglobin. A biologic fenton reagent.

SM Sadrzadeh, E Graf, SS Panter, PE Hallaway… - Journal of Biological …, 1984 - ASBMB
Iron and iron compounds may facilitate hydroxyl-radical generation from activated oxygen
species. Earlier work on the generation of this radical has been focused on simple, low-…

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

…, C Desnuelle, MH Soriani, J Dorst, E Graf… - Nature …, 2015 - nature.com
Amyotrophic lateral sclerosis (ALS) is a genetically heterogeneous neurodegenerative
syndrome hallmarked by adult-onset loss of motor neurons. We performed exome sequencing of …

Iron-catalyzed hydroxyl radical formation. Stringent requirement for free iron coordination site.

E Graf, JR Mahoney, RG Bryant, JW Eaton - Journal of Biological Chemistry, 1984 - Elsevier
The catalysis by iron of the formation of reactive oxygen species in biological systems has
been well documented. In this present study, we have investigated the hypothesis that iron-…