Abstract Development of new approaches for treatment of invasive fungal infections
encompasses new delivery systems for approved and investigational compounds, as well as …

… He classified his results in five study areas, designated from A to E; the first four areas were
located in Guatemala and the last area, E, was located in Nicaragua. Area A, with the highest …

Caspofungin is a new broad-spectrum antifungal drug. A multicenter, double-blind, randomized
trial was conducted to assess the efficacy, safety, and tolerability of caspofungin relative …

… MD a , Eduardo Gotuzzo MD b , Eduardo G Arathoon MD c , L.Miguel Noriega MD d , Nicholas
A Kartsonis MD e , Robert J Lupinacci MS e , Juanita M Smietana e , Mark J DiNubile MD …

Caspofungin is an antifungal agent of the novel echinocandin class. We investigated its efficacy,
safety, and tolerability as therapy for oropharyngeal and/or esophageal candidiasis in a …

The prevalence of fungal infections has increased significantly over the past few decades.
Candida and Aspergillus spp. are the most common fungal pathogens due to recent changes …

Background Violence against women by their male intimate partners (IPV) during pregnancy
may lead to negative pregnancy outcomes. We examined the role of IPV as a potential risk …

Histoplasmosis is an important cause of mortality in patients with AIDS, especially in
countries with limited access to antiretroviral therapies and diagnostic tests. However, many …

Coccidioidomycosis (or valley fever) is a fungal disease with high morbidity and mortality
that affects tens of thousands of people each year. This infection is caused by two sibling …

The pharmacokinetics of fluconazole, a new oral azole, were evaluated in cerebrospinal
fluid and sera of eight patients with coccidioidal meningitis. At a dose of 50 mg/day, peak …