A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
…, TT Valle, L Kinnunen, GR Abecasis, EW Pugh… - science, 2007 - science.org
Identifying the genetic variants that increase the risk of type 2 diabetes (T2D) in humans has
been a formidable challenge. Adopting a genome-wide association strategy, we genotyped …
been a formidable challenge. Adopting a genome-wide association strategy, we genotyped …
A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4
Case-parent trios were used in a genome-wide association study of cleft lip with and without
cleft palate. SNPs near two genes not previously associated with cleft lip with and without …
cleft palate. SNPs near two genes not previously associated with cleft lip with and without …
Detectable clonal mosaicism from birth to old age and its relationship to cancer
…, CP McHugh, H Ling, KN Hetrick, EW Pugh… - Nature …, 2012 - nature.com
We detected clonal mosaicism for large chromosomal anomalies (duplications, deletions
and uniparental disomy) using SNP microarray data from over 50,000 subjects recruited for …
and uniparental disomy) using SNP microarray data from over 50,000 subjects recruited for …
[BOOK][B] Building IBM: shaping an industry and its technology
EW Pugh - 2009 - books.google.com
… In reviewing the first of these books, the Boston Globe said, “Pugh's book is to good business
magazine journalism as Jane Austen is to New Yorker fiction." That accolade seems even …
magazine journalism as Jane Austen is to New Yorker fiction." That accolade seems even …
Genetic variants near TIMP3 and high-density lipoprotein–associated loci influence susceptibility to age-related macular degeneration
…, M Sanchez-Salorio, EW Pugh… - Proceedings of the …, 2010 - National Acad Sciences
We executed a genome-wide association scan for age-related macular degeneration (AMD)
in 2,157 cases and 1,150 controls. Our results validate AMD susceptibility loci near CFH (P …
in 2,157 cases and 1,150 controls. Our results validate AMD susceptibility loci near CFH (P …
[PDF][PDF] A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma
Three genetic loci for lung cancer risk have been identified by genome-wide association
studies (GWAS), but inherited susceptibility to specific histologic types of lung cancer is not well …
studies (GWAS), but inherited susceptibility to specific histologic types of lung cancer is not well …
Quality control and quality assurance in genotypic data for genome‐wide association studies
Genome‐wide scans of nucleotide variation in human subjects are providing an increasing
number of replicated associations with complex disease traits. Most of the variants detected …
number of replicated associations with complex disease traits. Most of the variants detected …
Genomewide association study for susceptibility genes contributing to familial Parkinson disease
…, JC Latourelle, AL DeStefano, C Halter, EW Pugh… - Human genetics, 2009 - Springer
Five genes have been identified that contribute to Mendelian forms of Parkinson disease (PD);
however, mutations have been found in fewer than 5% of patients, suggesting that …
however, mutations have been found in fewer than 5% of patients, suggesting that …
[BOOK][B] IBM's 360 and Early 370 Systems
EW Pugh, LR Johnson, JH Palmer - 1991 - books.google.com
No new product offering has had greater impact on the computer industry than the IBM
System/360. IBM's 360 and Early 370 Systems describes the creation of this remarkable system …
System/360. IBM's 360 and Early 370 Systems describes the creation of this remarkable system …
Common variants in the GDF5-UQCC region are associated with variation in human height
Identifying genetic variants that influence human height will advance our understanding of
skeletal growth and development. Several rare genetic variants have been convincingly and …
skeletal growth and development. Several rare genetic variants have been convincingly and …