While mechanobiological processes employ diverse mechanisms, at their heart are force-induced
perturbations in the structure and dynamics of molecules capable of triggering …

… We are grateful to the current members of the Haswell lab for insightful comments on this
review while it was in preparation. Our current work on MS ion channels in plants is supported …

The ability to sense and respond to a wide variety of mechanical stimuli—gravity, touch,
osmotic pressure, or the resistance of the cell wall—is a critical feature of every plant cell, …

Chromatin remodeling is required for efficient transcription of eukaryotic genes. In a genetic
selection for budding yeast mutants that were defective in induction of the phosphate-…

Background Mechanosensitive (MS) ion channels provide a mechanism for the perception
of mechanical stimuli such as sound, touch, and osmotic pressure. The bacterial MS ion …

In bacterial and animal systems, mechanosensitive (MS) ion channels are thought to mediate
the perception of pressure, touch, and sound [1–3]. Although plants respond to a wide …

… This work was funded by NSF MCB1253103 and NIH 2R01GM084211 to ES Haswell and
by the Monsanto Excellence Fund Fellowship to ES Hamilton. We acknowledge M. Wilson …

There is increasing evidence that all cells sense mechanical forces in order to perform their
functions. In animals, mechanotransduction has been studied during the establishment of …

In animals, PIEZOs are plasma membrane–localized cation channels involved in diverse
mechanosensory processes. We investigated PIEZO function in tip-growing cells in the moss …

… We are extremely grateful for the experimental and intellectual contributions of past and
present members of the Haswell lab. Our work is currently supported by National Science …