User profiles for E. R. Flores
Elsa FloresMoffitt Cancer Center Verified email at moffitt.org Cited by 9785 |
p63 and p73 are required for p53-dependent apoptosis in response to DNA damage
The tumour-suppressor gene p53 is frequently mutated in human cancers and is important in
the cellular response to DNA damage 1 , 2 . Although the p53 family members p63 and p73 …
the cellular response to DNA damage 1 , 2 . Although the p53 family members p63 and p73 …
Role for the p53 homologue p73 in E2F-1-induced apoptosis
…, AC Phillips, RS Seelan, DI Smith, W Liu, ER Flores… - Nature, 2000 - nature.com
The transcription factor E2F-1 induces both cell-cycle progression and, in certain settings,
apoptosis. E2F-1 uses both p53-dependent and p53-independent pathways to kill cells 1 , 2 , …
apoptosis. E2F-1 uses both p53-dependent and p53-independent pathways to kill cells 1 , 2 , …
[PDF][PDF] Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family
p63 and p73 are functionally and structurally related to the tumor suppressor p53. However,
their own role in tumor suppression is unclear. Given the p53-like properties of p63 and p73, …
their own role in tumor suppression is unclear. Given the p53-like properties of p63 and p73, …
TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs
… Elsa Flores and colleagues now show that TAp63, a member of the p53 family of tumour
suppressors, suppresses tumorigenesis and metastasis by directly controlling the expression of …
suppressors, suppresses tumorigenesis and metastasis by directly controlling the expression of …
Sulfide oxidation under chemolithoautotrophic denitrifying conditions
…, P Rowlette, ER Flores… - Biotechnology and …, 2006 - Wiley Online Library
Chemolithoautotrophic denitrifying microorganisms oxidize reduced inorganic sulfur
compounds coupled to the reduction of nitrate as an electron acceptor. These denitrifiers can be …
compounds coupled to the reduction of nitrate as an electron acceptor. These denitrifiers can be …
The human papillomavirus type 16 E7 oncogene is required for the productive stage of the viral life cycle
ER Flores, BL Allen-Hoffmann, D Lee… - Journal of …, 2000 - Am Soc Microbiol
The production of the human papillomavirus type 16 (HPV-16) is intimately tied to the
differentiation of the host epithelium that it infects. Infection occurs in the basal layer of the …
differentiation of the host epithelium that it infects. Infection occurs in the basal layer of the …
[PDF][PDF] Genomic, pathway network, and immunologic features distinguishing squamous carcinomas
This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing
molecular features of squamous cell carcinomas (SCCs) from five sites associated with …
molecular features of squamous cell carcinomas (SCCs) from five sites associated with …
[PDF][PDF] TAp63 prevents premature aging by promoting adult stem cell maintenance
The cellular mechanisms that regulate the maintenance of adult tissue stem cells are still
largely unknown. We show here that the p53 family member, TAp63, is essential for …
largely unknown. We show here that the p53 family member, TAp63, is essential for …
Evidence for a switch in the mode of human papillomavirus type 16 DNA replication during the viral life cycle
ER Flores, PF Lambert - Journal of virology, 1997 - Am Soc Microbiol
The study of human papillomavirus type 16 (HPV-16) replication has been impaired because
of the lack of a cell culture system that stably maintains viral replication. Recently, cervical …
of the lack of a cell culture system that stably maintains viral replication. Recently, cervical …
Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function
A De Vries, ER Flores, B Miranda… - Proceedings of the …, 2002 - National Acad Sciences
The p53 tumor suppressor gene is the most frequently mutated gene in human cancers, and
germ-line p53 mutations cause a familial predisposition for cancer. Germ-line or sporadic …
germ-line p53 mutations cause a familial predisposition for cancer. Germ-line or sporadic …