730 LONG & DA WID sized by RNA polymerase I (8) and is then processed in several steps
to yield mature rRNA (9). Developmental regulation of rRNA synthesis oc curs in certain …

… In mouse NK cells, SLP-76 is also required for NKG2D-dependent activation, but less so
for killing of the sensitive YAC-1 target cells (89, 90), perhaps due to redundant signaling …

… Second, they do so by recruiting phosphatases through an immunoreceptor tyrosine-based
inhibition motif (ITIM). Finally, inhibition can target different activation pathways but requires …

Natural killer (NK)–cell recognition of infected or neoplastic cells can induce cytotoxicity and
cytokine secretion. So far, it has been difficult to assess the relative contribution of multiple …

… so that wavelengths from 499 to 670 nm were acquired in a single pass. The pinhole was
adjusted so that optic slices of approximately 2 μm were acquired. Scan speed was set so that …

… The predicted transmembrane region that includes an arginine residue and the long
cytoplasmic tail with a single ITIM are also unique. Therefore, KIR2DL4 has features typical of both …

… and the strong synergies among activation signals described here, it is remarkable that
inhibitory receptor engagement by MHC class I on target cells can prevent cytotoxicity so …

… receptor family have a 9500 Euclid Avenue long cytoplasmic tail, while others have a short
form … Vitale, M., Bottino, C., Moretta, L., Moretta, A., and Long, EO clones and ability to mediate …

… lymphocytes and spleen, longer exposures revealed p58 … p58 cytoplasmic tails have a longer
spacing between the two YxxL … Thus, so far, there is no evidence for reassortment of extra- …

… Some of these components are dedicated to ligand binding, while other subunits with
long cytosolic tails contain immunoreceptor tyrosine-based activation motifs (ITAMs) that are …