Phenotypic variation is traditionally parsed into components that are directed by genetic and
environmental variation. The line between these two components is blurred by inherited …

Recent results from diverse organisms point to a self-reinforcing network of interactions
among the three best-characterized covalent modifications that mark heterochromatin: histone …

The development of genetic tools to alter DNA methylation has led to a deeper understanding
of the importance of DNA modification in the life strategies of different eukaryotic organisms…

Sequence similarity and profile searching tools were used to analyze the genome sequences
of Arabidopsis thaliana, Saccharomyces cerevisiae, Schizosaccharomyces pombe, …

We have developed a method for constructing genomic libraries enriched for telomeric DNA
sequences, enabling the isolation of telomeres from higher eukaryotic organisms with large …

Altering cytosine methylation by genetic means leads to a variety of developmental defects
in mice 1, plants 2, 3, 4, 5 and fungi 6, 7. Deregulation of cytosine methylation also has a role …

Three DNA hypomethylation mutants of the flowering plant Arabidopsis thaliana were isolated
by screening mutagenized populations for plants containing centromeric repetitive DNA …

{1} One day as I was sitting alone in my study surrounded by books on all kinds of subjects,
devoting myself to literary studies, my usual habit, my mind dwelt at length on the weighty …

We describe the isolation and characterization of two missense mutations in the cytosine-DNA-methyl-transferase
gene, MET1, from the flowering plant Arabidopsis thaliana. Both …

MicroRNA-155 (miR-155) is frequently upregulated in various types of human cancer; however,
its role in cancer angiogenesis remains unknown. Here, we demonstrate the role of miR-…