User profiles for E. E. Fannin
 | Emily E FanninWake Forest School of Medicine Verified email at wakehealth.edu Cited by 586 |
[HTML][HTML] Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C
Persistent infections with hepatitis B virus (HBV) or hepatitis C virus (HCV) account for the
majority of cases of hepatic cirrhosis and hepatocellular carcinoma (HCC) worldwide. Small, …
majority of cases of hepatic cirrhosis and hepatocellular carcinoma (HCC) worldwide. Small, …
MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes
MicroRNAs (miRNAs) have emerged as biomarkers of metabolic status, etiological factors
in complex disease, and promising drug targets. Recent reports suggest that miRNAs are …
in complex disease, and promising drug targets. Recent reports suggest that miRNAs are …
[HTML][HTML] Addressing bias in small RNA library preparation for sequencing: a new protocol recovers microRNAs that evade capture by current methods
Recent advances in sequencing technology have helped unveil the unexpected complexity
and diversity of small RNAs. A critical step in small RNA library preparation for sequencing is …
and diversity of small RNAs. A critical step in small RNA library preparation for sequencing is …
[HTML][HTML] Beta cell 5′-shifted isomiRs are candidate regulatory hubs in type 2 diabetes
J Baran-Gale, EE Fannin, CL Kurtz, P Sethupathy - PloS one, 2013 - journals.plos.org
Next-generation deep sequencing of small RNAs has unveiled the complexity of the microRNA
(miRNA) transcriptome, which is in large part due to the diversity of miRNA sequence …
(miRNA) transcriptome, which is in large part due to the diversity of miRNA sequence …
[HTML][HTML] Inhibition of miR-29 has a significant lipid-lowering benefit through suppression of lipogenic programs in liver
CL Kurtz, EE Fannin, CL Toth, DS Pearson… - Scientific reports, 2015 - nature.com
MicroRNAs (miRNAs) are important regulators and potential therapeutic targets of
metabolic disease. In this study we show by in vivo administration of locked nucleic acid (LNA) …
metabolic disease. In this study we show by in vivo administration of locked nucleic acid (LNA) …
[HTML][HTML] Characterization of multicellular breast tumor spheroids using image data-driven biophysical mathematical modeling
Multicellular tumor spheroid (MCTS) systems provide an in vitro cell culture model system
which mimics many of the complexities of an in vivo solid tumor and tumor microenvironment, …
which mimics many of the complexities of an in vivo solid tumor and tumor microenvironment, …
Massively differential bias between two widely used Illumina library preparation methods for small RNA sequencing
Recent advances in sequencing technology have helped unveil the unexpected complexity
and diversity of small RNAs. A critical step in small RNA library preparation for sequencing is …
and diversity of small RNAs. A critical step in small RNA library preparation for sequencing is …
Abstract P1-06-05: Image driven biophysical mathematical modeling of multicellular breast tumor spheroids
Introduction: Conventional 2D monolayer cell culture methods have distinct weaknesses in
mimicking in vivo tumors as they ignore major phenotypic physical tumor microenvironment (…
mimicking in vivo tumors as they ignore major phenotypic physical tumor microenvironment (…
[PDF][PDF] ONLINE SUPPLEMENTAL INFORMATION
…, M Honda, D Yamane, T Masaki, EE Fannin… - scienceopen.com
Supplemental Figure 1. Example of a tRNA coverage plot for small RNAs detected in
nonmalignant tissue from HBV-infected subject 6. Each line in the coverage plot represents tRNA …
nonmalignant tissue from HBV-infected subject 6. Each line in the coverage plot represents tRNA …
On the use of empirical methods for assessment of filters in embankment dams
H Rönnqvist, J Fannin, P Viklander - Géotechnique Letters, 2014 - icevirtuallibrary.com
… The average value of the EE boundary is D 15 = 8ṡ5 mm (Fig. 6). More specifically, D 15
is 7ṡ0 mm for 9 dams with 0ṡ3 mm < d 95 < 2 mm (which includes the Appendix dam F), 6ṡ7 …
is 7ṡ0 mm for 9 dams with 0ṡ3 mm < d 95 < 2 mm (which includes the Appendix dam F), 6ṡ7 …