User profiles for D. Weitz
David A. WeitzProfessor of Physics and Applied Physics, Harvard University Verified email at seas.harvard.edu Cited by 161640 |
Droplet microfluidics for high-throughput biological assays
Droplet microfluidics offers significant advantages for performing high-throughput screens
and sensitive assays. Droplets allow sample volumes to be significantly reduced, leading to …
and sensitive assays. Droplets allow sample volumes to be significantly reduced, leading to …
[HTML][HTML] Designer emulsions using microfluidics
…, JW Kim, A Fernandez-Nieves, CJ Martinez, DA Weitz - Materials Today, 2008 - Elsevier
We describe new developments for the controlled fabrication of monodisperse emulsions
using microfluidics. We use glass capillary devices to generate single, double, and higher …
using microfluidics. We use glass capillary devices to generate single, double, and higher …
The cell as a material
To elucidate the dynamic and functional role of a cell within the tissue it belongs to, it is
essential to understand its material properties. The cell is a viscoelastic material with highly …
essential to understand its material properties. The cell is a viscoelastic material with highly …
Monodisperse double emulsions generated from a microcapillary device
Double emulsions are highly structured fluids consisting of emulsion drops that contain
smaller droplets inside. Although double emulsions are potentially of commercial value, …
smaller droplets inside. Although double emulsions are potentially of commercial value, …
[PDF][PDF] Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets
…, N Kamitaki, EM Martersteck, JJ Trombetta, DA Weitz… - Cell, 2015 - cell.com
… d Drop-seq enables highly parallel analysis of individual cells by RNA-seq d Drop-seq …
synthesis to generate the UMI on each oligo (Figure 1D); finally, an oligo-dT sequence (T30) is …
synthesis to generate the UMI on each oligo (Figure 1D); finally, an oligo-dT sequence (T30) is …
Colloidosomes: selectively permeable capsules composed of colloidal particles
We present an approach to fabricate solid capsules with precise control of size, permeability,
mechanical strength, and compatibility. The capsules are fabricated by the self-assembly of …
mechanical strength, and compatibility. The capsules are fabricated by the self-assembly of …
[PDF][PDF] Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells
It has long been the dream of biologists to map gene expression at the single-cell level.
With such data one might track heterogeneous cell sub-populations, and infer regulatory …
With such data one might track heterogeneous cell sub-populations, and infer regulatory …
Geometrically mediated breakup of drops in microfluidic devices
… 2(d). An enlargement of the drop at its point of maximum extension " ‘e= we … out of the
junction in (d). At maximum extension, shown in (e), the extended length ‘e and width we give " …
junction in (d). At maximum extension, shown in (e), the extended length ‘e and width we give " …
Three-dimensional direct imaging of structural relaxation near the colloidal glass transition
…, JC Crocker, AC Levitt, A Schofield, DA Weitz - Science, 2000 - science.org
Confocal microscopy was used to directly observe three-dimensional dynamics of particles
in colloidal supercooled fluids and colloidal glasses. The fastest particles moved …
in colloidal supercooled fluids and colloidal glasses. The fastest particles moved …
Single-cell analysis and sorting using droplet-based microfluidics
We present a droplet-based microfluidics protocol for high-throughput analysis and sorting
of single cells. Compartmentalization of single cells in droplets enables the analysis of …
of single cells. Compartmentalization of single cells in droplets enables the analysis of …