Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of
alleles, including common alleles of small effect that might be detected by genome-wide …

Schizophrenia is a severe mental disorder with a lifetime risk of about 1%, characterized by
hallucinations, delusions and cognitive deficits, with heritability estimated at up to 80% 1 , 2 . …

We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old
hunter-gatherers from Luxembourg and Sweden. We analysed these and other …

Here we report the Simons Genome Diversity Project data set: high quality genomes from 300
individuals from 142 diverse populations. These genomes include at least 5.8 million base …

A small number of rare, recurrent genomic copy number variants (CNVs) are known to
substantially increase susceptibility to schizophrenia. As a consequence of the low fecundity in …

… [13] reported a decreased erythrocyte ALA-D activity in patients with BEN and in 32% of their
… The role of variations in LCAT, ALA-D and CYP2D6 activity in the pathogenesis of BEN still …

Using principal component (PC) analysis, we studied the genetic constitution of 3,112
individuals from Europe as portrayed by more than 270,000 single nucleotide polymorphisms (…

… Both the A/C and B/D duplication architectures exhibit inverted orientations compared
with … (E) Maximum likelihood tree of the 16p12 duplication locus [duplication D in (B) to (D)] …

Many common illnesses, for reasons that have not been identified, differentially affect men
and women. For instance, the autoimmune diseases systemic lupus erythematosus (SLE) and …

Schizophrenia is a devastating psychiatric illness with high heritability. Brain structure and
function differ, on average, between people with schizophrenia and healthy individuals. As …