Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen

JD Radolf, RK Deka, A Anand, D Šmajs… - Nature Reviews …, 2016 - nature.com
The past two decades have seen a worldwide resurgence in infections caused by Treponema
pallidum subsp. pallidum, the syphilis spirochete. The well-recognized capacity of the …

A Novel Treponema pallidum Antigen, TP0136, Is an Outer Membrane Protein That Binds Human Fibronectin

…, A Rogers, P Matejková, D Šmajs… - Infection and …, 2008 - Am Soc Microbiol
The antigenicity, structural location, and function of the predicted lipoprotein TP0136 of
Treponema pallidum subsp. pallidum were investigated based on previous screening studies …

[HTML][HTML] Whole Genome Sequences of Three Treponema pallidum ssp. pertenue Strains: Yaws and Syphilis Treponemes Differ in Less than 0.2% of the Genome …

…, E Sodergren, GM Weinstock, D Šmajs - PLoS neglected …, 2012 - journals.plos.org
… -quality whole genome sequences of three TPE strains (Samoa D, CDC-2, Gauthier) were
… The whole genome nucleotide divergence (d A ) between TPA and TPE subspecies was 4.7 …

Macrolide treatment failure in a case of secondary syphilis: a novel A2059G mutation in the 23S rRNA gene of Treponema pallidum subsp. pallidum

…, GM Weinstock, D Šmajs - Journal of medical …, 2009 - microbiologyresearch.org
We report an occurrence of treatment failure after oral spiramycin therapy in a man with
secondary syphilis and a reported penicillin and tetracycline allergy. Molecular detection …

[HTML][HTML] Genetic diversity in Treponema pallidum: implications for pathogenesis, evolution and molecular diagnostics of syphilis and yaws

D Šmajs, SJ Norris, GM Weinstock - Infection, Genetics and Evolution, 2012 - Elsevier
… paraluiscuniculi and TPE genomes (eg tprA,C,D,F,I,J,K,L; recQ; TP0136; tp92, arp; mcp; and
hypothetical genes) may be involved in determination of syphilis-specific symptomatology (…

S-layers on cell walls of cyanobacteria

J Šmarda, D Šmajs, J Komrska, V Krzyžánek - Micron, 2002 - Elsevier
… In general, each S-layer exhibits one of four possible 2-D lattice types: oblique (p1 or p2
symmetry), triangle (p3 symmetry), square (p4 symmetry) or hexagonal (p6 symmetry). The S-…

Characterization of Colicin S4 and Its Receptor, OmpW, a Minor Protein of the Escherichia coli Outer Membrane

H Pilsl, D Smajs, V Braun - Journal of bacteriology, 1999 - Am Soc Microbiol
ABSTRACT Analysis of the nucleotide sequence of an Escherichia coli colicin S4 determinant
revealed 76% identity to the pore-forming domain of the colicin A protein, 77% identity to …

[HTML][HTML] Whole Genome Sequence of Treponema pallidum ssp. pallidum, Strain Mexico A, Suggests Recombination between Yaws and Syphilis Strains

…, L Chen, X Qin, DM Muzny, GM Weinstock, D Šmajs - 2012 - journals.plos.org
… In addition to TPA strains, the Mexico A genome sequence was also compared with whole
genome sequences of three TPE strains including Samoa D (GenBank acc. no. CP002374.1), …

[HTML][HTML] Escherichia colistrains of phylogenetic group B2 and D and bacteriocin production are associated with advanced colorectal neoplasia

D Kohoutova, D Smajs, P Moravkova, J Cyrany… - BMC infectious …, 2014 - Springer
… coli phylogroup D was found in patients with CRC, when compared to controls, p = 0.044. A
… coli phylogroup D were isolated in biopsies of patients with right-sided CRC. A statistically …

[HTML][HTML] Complete genome sequence of Treponema pallidum ssp. pallidumstrain SS14 determined with oligonucleotide arrays

P Matějková, M Strouhal, D Šmajs, SJ Norris… - BMC microbiology, 2008 - Springer
… Selection of these regions was focused on possible variable regions in SS14/Nichols
hybridization experiments (D. Šmajs, GM Weinstock, unpublished results) using a microarray of …